• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Lower extremity peripheral artery disease (PAD) affects> 230 million adults worldwide and is
associated with increased risk of various adverse clinical outcomes (other cardiovascular …

Diabetic foot disease results in a major global burden for patients and the health care
system. The International Working Group on the Diabetic Foot (IWGDF) has been producing …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

Multiple disciplines are involved in the management of diabetic foot disease, and a common
vocabulary is essential for clear communication. Based on the systematic reviews of the …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

As a progressive disease process, early diagnosis and ongoing monitoring and treatment of
lower limb peripheral artery disease (PAD) is critical to reduce the risk of diabetes‐related …

Nontraumatic lower-extremity amputation is a devastating complication of peripheral artery
disease (PAD) with a high mortality and medical expenditure. There are≈ 150 000 …

Diabetic foot ulcers (DFU) are one of the most challenging complications of diabetes. Up to
one-third of patients with diabetes mellitus (DM) may suffer from DFUs during their life. DFU …

Diabetes related foot complications have become a major cause of morbidity and are
implicated in most major and minor amputations globally. Approximately 50% of people with …