Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

Health professionals are encouraged to take the Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …

Importance Low-dose aspirin is used for primary cardiovascular disease prevention and
may have benefits for colorectal cancer prevention. Objective To review the benefits and …

Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …

Alzheimer disease (AD) is characterized by wide heterogeneity in cognitive and behavioural
syndromes, risk factors and pathophysiological mechanisms. Addressing this phenotypic …

Women spend approximately one-third of their lives with menopause, which occurs around
50 years of age. It is now appreciated that several important metabolic and cardiovascular …

In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

Background A one-dose-fits-all approach to use of aspirin has yielded only modest benefits
in long-term prevention of cardiovascular events, possibly due to underdosing in patients of …

For several decades, the role of hormone-replacement therapy (HRT) has been debated.
Early observational data on HRT showed many benefits, including a reduction in coronary …

Purpose—The aim of this statement is to summarize data on stroke risk factors that are
unique to and more common in women than men and to expand on the data provided in …