In this review, we describe a detailed investigation about the structural variations and
relative activity of 1, 8-naphthalimide based intercalators and anticancer agents. The 1, 8 …

Selenium (Se)-containing compounds have emerged as potential therapeutic agents for the
treatment of a range of diseases. Through tremendous effort, considerable knowledge has …

The chemical and biological interest in this element and the molecules bearing selenium
has been exponentially growing over the years. Selenium, formerly designated as a toxin …

Incorporation of selenium (Se) atom into small molecules can substantially enhance their
antioxidant, anti-inflammatory, antimutagenic, antitumoral or chemopreventive, antiviral …

A series of seleno-biotin analogs were synthesized and their anticancer activity and mode of
action were assessed using ovarian cancer cells. Compound 2, out of the other analogs, in …

The association of leishmaniasis and malignancies in human and animal models has been
highlighted in recent years. The misdiagnosis of coexistence of leishmaniasis and cancer …

As the number of cases and cancer-related deaths are projected to rise in upcoming years, it
is urgent to find ways to prevent or treat cancer. As such, food-derived products have gained …

Conventional chemotherapy against leishmaniasis includes agents exhibiting considerable
toxicity. In addition, reports of drug resistance are not uncommon. Thus, safe and effective …

A series of seleno-containing polyfunctionalized compounds was synthesized exploring
cyanohydrin chemistry, including α-hydroxy esters, α-hydroxy acids, 1, 2-diols, and 1, 2 …

Background: The family of DNA topoisomerases comprises a group of enzymes that catalyse
the induction of topological changes to DNA. These enzymes play a role in the cell …