[HTML][HTML] The impact of Di-(2-ethylhexyl) Phthalate and Mono (2-ethylhexyl) Phthalate in placental development, function, and pathophysiology

LD Martínez-Razo, A Martínez-Ibarra… - Environment …, 2021 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a chemical widely distributed in the
environment as is extensively used in the plastic industry. DEHP is considered an endocrine …

Placenta disrupted: endocrine disrupting chemicals and pregnancy

J Gingrich, E Ticiani, A Veiga-Lopez - Trends in Endocrinology & …, 2020 - cell.com
Endocrine disrupting chemicals (EDCs) are chemicals that can interfere with normal
endocrine signals. Human exposure to EDCs is particularly concerning during vulnerable …

Fetoplacental vasculature as a model to study human cardiovascular endocrine disruption

M Lorigo, E Cairrao - Molecular aspects of medicine, 2022 - Elsevier
Increasing evidence has associated the exposure of endocrine-disrupting chemicals (EDCs)
with the cardiovascular (CV) system. This exposure is particularly problematic in a sensitive …

A mechanism for the effect of endocrine disrupting chemicals on placentation

C Yang, G Song, W Lim - Chemosphere, 2019 - Elsevier
Numerous recent studies have shown that endocrine disrupting chemicals (EDCs) in the
body of pregnant women can pass through the placenta and be exposed to the fetus …

Impacts of bisphenol A (BPA) and phthalate exposures on epigenetic outcomes in the human placenta

RS Strakovsky, SL Schantz - Environmental epigenetics, 2018 - academic.oup.com
The placenta guides fetal growth and development. Bisphenol A (BPA) and phthalates are
widespread environmental contaminants and endocrine disruptors, and the placental …

[HTML][HTML] Neurotoxicity and the potential molecular mechanisms of mono-2-ethylhexyl phthalic acid (MEHP) in zebrafish

Y Liu, WB Huo, JY Deng, QP Tang, JX Wang… - Ecotoxicology and …, 2023 - Elsevier
Abstract Mono-2-ethylhexyl phthalic acid (MEHP) is the most toxic metabolite of plasticizer di-
2-ethylhexyl phthalic acid (DEHP), and there is limited information available on the effects of …

The Role of Peroxisome Proliferator–Activated Receptor Gamma () in Mono(2-ethylhexyl) Phthalate (MEHP)-Mediated Cytotrophoblast Differentiation

H Shoaito, J Petit, A Chissey, N Auzeil… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Phthalates are environmental contaminants commonly used as plasticizers in
polyvinyl chloride (PVC) products. Recently, exposure to phthalates has been associated …

Plastics and plastic additives as inducers of oxidative stress

E Pérez-Albaladejo, M Solé, C Porte - Current Opinion in Toxicology, 2020 - Elsevier
As plastics in the environment break down to smaller particles, contain additives, trap
environmental pollutants and cross cell membranes, there is growing concern about the …

Exposure to endocrine disrupting chemicals impacts immunological and metabolic status of women during pregnancy

AK Merrill, M Sobolewski, M Susiarjo - Molecular and Cellular …, 2023 - Elsevier
Pregnancy is a unique physiological window for maternal and fetal health. Disorders that
arise during pregnancy influence the survival and health outcomes of mother and baby …

Placental outcomes of phthalate exposure

GR Warner, RS Dettogni, IC Bagchi, JA Flaws… - Reproductive …, 2021 - Elsevier
Proper placental development and function relies on hormone receptors and signaling
pathways that make the placenta susceptible to disruption by endocrine disrupting …