Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

The pandemic coronavirus disease 2019 (COVID-19), caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading globally …

Abstract Design of micro-or nanocarriers for drug delivery has primarily been focused on
properties such as hydrophobicity, biodegradability, size, shape, surface charge, and …

Heparin is an anticoagulant medication that was discovered in 1917 and used in clinic since
1935. Low molecular weight heparins (LMWHs) represent a refined use of heparin as …

Our objective is to reveal the molecular mechanism of the anti-inflammatory action of low-
molecular-weight heparin (LMWH) based on its influence on the activity of two key cytokines …

Heparin mimetics are synthetic and semi-synthetic compounds that are highly sulfated,
structurally distinct analogues of glycosaminoglycans. These mimetics are often rationally …

Polysaccharide-based materials created by physical processes have received considerable
attention for biomedical applications. These structures are often made by associating …

Severe imbalance in iron metabolism among SARS-CoV-2 infected patients is prominent in
every symptomatic (mild, moderate to severe) clinical phase of COVID-19. Phase-I–Hypoxia …

Glycosaminoglycans (GAGs) and their oligosaccharides have attracted extensive attention
because of their wide applications in cosmetics, health, and clinical treatment of, for …

The postthrombotic syndrome (PTS) is chronic venous insufficiency secondary to a prior
deep vein thrombosis (DVT). It is the most common complication of venous …