Arsenic and selenium are readily metabolized by prokaryotes, participating in a full range of
metabolic functions including assimilation, methylation, detoxification, and anaerobic …

NMR spectroscopy is a powerful tool for studying proteins and nucleic acids in solution. This
is illustrated by the fact that nearly half of all current RNA structures were determined by …

Methionine residues in proteins are susceptible to oxidation by reactive oxygen species, but
can be repaired via reduction of the resulting methionine sulfoxides by methionine-S …

The nuclear phosphoprotein La was identified as an autoantigen in patients with systemic
lupus erythematosus and Sjogren's syndrome. La binds to and protects the UUU OH 3 …

Despite their crucial role in the stabilization of biomolecular structures and their almost
ubiquitous involvement in biomolecular reactions, such as enzymatic cleavage or ligand …

Selenocysteine (Sec) and pyrrolysine (Pyl) are known as the 21st and 22nd amino acids in
protein. Both are encoded by codons that normally function as stop signals. Sec …

The La protein is a ubiquitous nuclear phosphoprotein that recognizes the 3′ uridylates
found in all newly synthesized RNA polymerase III transcripts. La binding stabilizes these …

Abstract Motivation: Incorporation of selenocysteine (Sec) into proteins in response to UGA
codons requires a cis-acting RNA structure, Sec insertion sequence (SECIS) element …

In all three kingdoms of life, SelB is a specialized translation elongation factor responsible
for the cotranslational incorporation of selenocysteine into proteins by recoding of a UGA …

Selenium shares many chemical facets with sulphur but differs from it in the redox potential,
especially of the Se2−/S2− oxidation state. The higher chemical reactivity of the …