X-ray phase-contrast imaging: from pre-clinical applications towards clinics

A Bravin, P Coan, P Suortti - Physics in Medicine & Biology, 2012 - iopscience.iop.org
Phase-contrast x-ray imaging (PCI) is an innovative method that is sensitive to the refraction
of the x-rays in matter. PCI is particularly adapted to visualize weakly absorbing details like …

Dark-field computed tomography reaches the human scale

M Viermetz, N Gustschin, C Schmid… - Proceedings of the …, 2022 - National Acad Sciences
X-ray computed tomography (CT) is one of the most commonly used three-dimensional
medical imaging modalities today. It has been refined over several decades, with the most …

Recent advances in synchrotron-based hard x-ray phase contrast imaging

Y Liu, J Nelson, C Holzner, JC Andrews… - Journal of Physics D …, 2013 - iopscience.iop.org
Ever since the first demonstration of phase contrast imaging (PCI) in the 1930s by Frits
Zernike, people have realized the significant advantage of phase contrast over conventional …

General solution for quantitative dark-field contrast imaging with grating interferometers

M Strobl - Scientific reports, 2014 - nature.com
Grating interferometer based imaging with X-rays and neutrons has proven to hold huge
potential for applications in key research fields conveying biology and medicine as well as …

In-vivo dark-field and phase-contrast x-ray imaging

M Bech, A Tapfer, A Velroyen, A Yaroshenko… - Scientific reports, 2013 - nature.com
Novel radiography approaches based on the wave nature of x-rays when propagating
through matter have a great potential for improved future x-ray diagnostics in the clinics …

On the quantification of sample microstructure using single-exposure x-ray dark-field imaging via a single-grid setup

YY How, DM Paganin, KS Morgan - Scientific Reports, 2023 - nature.com
The size of the smallest detectable sample feature in an x-ray imaging system is usually
restricted by the spatial resolution of the system. This limitation can now be overcome using …

Pulmonary emphysema diagnosis with a preclinical small-animal x-ray dark-field scatter-contrast scanner

A Yaroshenko, FG Meinel, M Bech, A Tapfer… - Radiology, 2013 - pubs.rsna.org
Purpose To test the hypothesis that the joint distribution of x-ray transmission and dark-field
signals obtained with a compact cone-beam preclinical scanner with a polychromatic source …

On a dark-field signal generated by micrometer-sized calcifications in phase-contrast mammography

T Michel, J Rieger, G Anton, F Bayer… - Physics in Medicine …, 2013 - iopscience.iop.org
We show that a distribution of micrometer-sized calcifications in the human breast which are
not visible in clinical x-ray mammography at diagnostic dose levels can produce a significant …

X-ray Dark-field Radiography - In-Vivo Diagnosis of Lung Cancer in Mice

K Scherer, A Yaroshenko, DA Bölükbas, LB Gromann… - Scientific reports, 2017 - nature.com
Accounting for about 1.5 million deaths annually, lung cancer is the prevailing cause of
cancer deaths worldwide, mostly associated with long-term smoking effects. Numerous …

X-ray tensor tomography (a)

A Malecki, G Potdevin, T Biernath, E Eggl… - Europhysics …, 2014 - iopscience.iop.org
Here we introduce a new concept for x-ray computed tomography that yields information
about the local micro-morphology and its orientation in each voxel of the reconstructed 3D …