Traumatic brain injury: an overview of pathobiology with emphasis on military populations

I Cernak, LJ Noble-Haeusslein - Journal of Cerebral Blood …, 2010 - journals.sagepub.com
This review considers the pathobiology of non-impact blast-induced neurotrauma (BINT).
The pathobiology of traumatic brain injury (TBI) has been historically studied in experimental …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Large animal models of traumatic brain injury

R Vink - Journal of neuroscience research, 2018 - Wiley Online Library
Animal models are essential to gain a deeper understanding of the pathophysiology
associated with traumatic brain injury (TBI). Rodent models of TBI have proven highly …

Morphologic and biochemical characterization of brain injury in a model of controlled blast overpressure exposure

SI Svetlov, V Prima, DR Kirk, H Gutierrez… - Journal of Trauma …, 2010 - journals.lww.com
Objectives: Existing experimental approaches for studies of blast impact in small animals are
insufficient and lacking consistency. Here, we present a comprehensive model, with …

The importance of systemic response in the pathobiology of blast-induced neurotrauma

I Cernak - Frontiers in Neurology., 2010 - frontiersin.org
Due to complex injurious environment where multiple blast effects interact with the body
parallel, blast-induced neurotrauma is a unique clinical entity induced by systemic, local …

Blast injury from explosive munitions

I Cernak, J Savic, D Ignjatovic… - Journal of Trauma and …, 1999 - journals.lww.com
Methods One thousand three hundred and three patients injured by explosive munitions and
demonstrating extremity wounds without other penetrating injuries were admitted to the …

Cognitive deficits following blast injury-induced neurotrauma: possible involvement of nitric oxide

I Cernak, Z Wang, J Jiang, X Bian, J Savic - Brain Injury, 2001 - Taylor & Francis
Blast injuries, that is injuries caused by the complex pressure wave generated by some
explosions, show increasing frequency throughout the world. However, whether blast injury …

Neuropathology and pressure in the pig brain resulting from low-impulse noise exposure

A Säljö, F Arrhén, H Bolouri, M Mayorga… - Journal of …, 2008 - liebertpub.com
Military personnel are exposed to occupational levels of blast overpressure during training.
This study characterizes the pressure-time histories of air, underwater, and localized blast …

Biomarkers of blast-induced neurotrauma: profiling molecular and cellular mechanisms of blast brain injury

SI Svetlov, SF Larner, DR Kirk, J Atkinson… - Journal of …, 2009 - liebertpub.com
The nature of warfare in the 21st century has led to a significant increase in primary blast or
over-pressurization injuries to the whole body and head, which manifest as a complex of …

[HTML][HTML] Blast injuries and blast-induced neurotrauma: overview of pathophysiology and experimental knowledge models and findings

I Cernak - 2015 - europepmc.org
Explosions are physical phenomena that result in the sudden release of energy; they may
be chemical, nuclear, or mechanical. This process results in a near-instantaneous pressure …