Rho kinase inhibitors as a novel treatment for glaucoma and ocular hypertension

AP Tanna, M Johnson - Ophthalmology, 2018 - Elsevier
In an elegant example of bench-to-bedside research, a hypothesis that cells in the outflow
pathway actively regulate conventional outflow resistance was proposed in the 1990s and …

Primary open angle glaucoma and vascular risk factors: a review of population based studies from 1990 to 2019

A Grzybowski, M Och, P Kanclerz, C Leffler… - Journal of clinical …, 2020 - mdpi.com
Glaucoma is one of the leading causes of blindness worldwide, and as the proportion of
those over age 40 increases, so will the prevalence of glaucoma. The pathogenesis of …

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of …

G Mancia, R Kreutz, M Brunström, M Burnier… - Journal of …, 2023 - journals.lww.com
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

[PDF][PDF] 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of …

M Brunström, M Burnier… - Journal of …, 2023 - docred-strapi-cms-prod.s3.sa-east-1 …
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

The role of axonal transport in glaucoma

MS Dias, X Luo, VT Ribas, H Petrs-Silva… - International Journal of …, 2022 - mdpi.com
Glaucoma is a neurodegenerative disease that affects the retinal ganglion cells (RGCs) and
leads to progressive vision loss. The first pathological signs can be seen at the optic nerve …

Ocular blood flow as a clinical observation: Value, limitations and data analysis

A Harris, G Guidoboni, B Siesky, S Mathew… - Progress in retinal and …, 2020 - Elsevier
Alterations in ocular blood flow have been identified as important risk factors for the onset
and progression of numerous diseases of the eye. In particular, several population-based …

Glaucoma and blood pressure

M Leeman, P Kestelyn - Hypertension, 2019 - Am Heart Assoc
The pathogenesis of glaucoma is incompletely understood, but the death of axons grouped
together at the optic disc implies that this anatomic area is primarily involved. The typical …

Machine learning-based predictive modeling of surgical intervention in glaucoma using systemic data from electronic health records

SL Baxter, C Marks, TT Kuo, L Ohno-Machado… - American journal of …, 2019 - Elsevier
Purpose To predict the need for surgical intervention in patients with primary open-angle
glaucoma (POAG) using systemic data in electronic health records (EHRs). Design …

Nocturnal blood pressure dip and parapapillary choroidal microvasculature dropout in normal-tension glaucoma

JW Shin, YH Jo, MK Song, HJ Won, MS Kook - Scientific reports, 2021 - nature.com
Choroidal microvasculature dropout (CMvD) implies compromised optic nerve head
perfusion in glaucoma patients. However, there are conflicting findings whether office-hour …

U-shaped effect of blood pressure on structural OCT metrics and retinal perfusion in ophthalmologically healthy subjects

K Pappelis, NM Jansonius - Investigative ophthalmology & …, 2021 - iovs.arvojournals.org
Purpose: We wanted to investigate the association of blood pressure (BP) status with the
ganglion cell-inner plexiform layer (GCIPL) and retinal nerve fiber layer (RNFL) thickness of …