Cell penetrating peptides (CPPs), also known as protein transduction domains (PTDs), first
identified~ 25 years ago, are small, 6–30 amino acid long, synthetic, or naturally occurring …

Inflammation is a defense and protective response to multiple harmful stimuli. Over and
uncontrolled inflammation can lead to local tissues or even systemic damages and injuries …

Objectives Peptides and proteins represent great potential for modulating various cellular
processes including oxidative stress, inflammatory response, apoptosis and consequently …

Background Chronic low-grade inflammation and oxidative stress play important roles in the
development of obesity-induced cardiac hypertrophy. Here, we investigated the role of …

Oxidative stress has a considerable influence on endothelial cell dysfunction and
atherosclerosis. Acacetin, an anti‐inflammatory and antiarrhythmic, is frequently used in the …

Inflammation is important and has been found to be an underlying cause in many acute and
chronic human diseases. Nuciferine, a natural alkaloid containing an aromatic ring, is found …

Reperfusion injury can exacerbate tissue damage in ischemic stroke, but little is known
about the mechanisms linking ROS to stroke severity. Here, we tested the hypothesis that …

Introduction Demyelination causes neurological deficits involving visual, motor, sensory
symptoms. Deregulation of several enzymes has been identified in demyelination, which …

To develop a strong HIV specific T-cell response, the HIV-1 Tat and Nef regulatory proteins
have been known as attractive antigenic candidates in vaccine design. A peptide …

Exposure to toxicants/stressors has been linked to the development of many human
diseases. They could affect various cellular components, such as DNA, proteins, lipids, and …