Abstract Histone deacetylase 6 (HDAC6) is a class IIb histone deacetylase that contains two
catalytic domains and a zinc-finger ubiquitin binding domain (ZnF-UBP) domain. The …

Simple Summary With 19.3 million new cancer cases worldwide and nearly 10.0 million
cancer-related deaths cancer is a global health challenge. Cancer is a disease caused by a …

Pancreatic adenocarcinoma is a malignancy with rising incidence and grim prognosis.
Despite improvements in therapeutics for treating metastatic pancreatic cancer, this disease …

Simple Summary Pancreatic cancer is a serious ongoing global health burden, with an
overall 5-year survival rate of less than 5%. One major hurdle in the treatment of this disease …

Mutations in the Krebs cycle enzyme IDH1 (isocitrate dehydrogenase (NADP (+)) 1) are
associated with better prognosis in gliomas. Though IDH1 mutant (IDH1R132H) tumors are …

Abstract mRNA export, translation, splicing, cleavage or capping determine mRNA stability,
which represents one of the primary aspects regulating gene expression and function. RNA …

Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown,
with ageing being the greatness risk factor. Methods: This new perspective evaluates the …

Background and Objectives: Malignant glioblastoma (GBM) is caused by abnormal
proliferation of glial cells, which are found in the brain. The therapeutic effects of surgical …

Liver cancer is a leading cause of cancer-related mortality globally. Since hepatitis virus
infections have been strongly associated with the incidence of liver cancer, studies …

Neuroblastoma is a pediatric cancer of neural crest cells. It develops most frequently in
nerve cells around the adrenal gland, although other locations are possible …