Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

High frequency oscillations (HFO) have a variety of characteristics: band-limited or broad-
band, transient burst-like phenomenon or steady-state. HFOs may be encountered under …

Why are people with focal epilepsy not continuously having seizures? Previous neuronal
signalling work has implicated gamma-aminobutyric acid balance as integral to seizure …

A better understanding of the mechanisms involved in human higher cortical functions
requires a detailed knowledge of neuronal connectivity between functional cortical regions …

Purpose Deep brain stimulation (DBS) of the thalamus is an emerging surgical option for
people with medically refractory epilepsy that is not suitable for resective surgery, or in …

In the last decade, single pulse electrical stimulation (SPES) has been used as an
investigational tool in the field of epilepsy surgery. Direct cortical stimulation applied at a …

Brain stimulation has emerged as an effective treatment for a wide range of neurological and
psychiatric diseases. Parkinson's disease, epilepsy, and essential tremor have FDA …

During non-rapid eye movement (NREM) sleep (stage N3), when consciousness fades,
cortico-cortical interactions are impaired while neurons are still active and reactive. Why is …

Epilepsy presurgical investigation may include focal intracortical single-pulse electrical
stimulations with depth electrodes, which induce cortico-cortical evoked potentials at distant …

Key to understanding the neuronal basis of consciousness is the characterization of the
neural signatures of changes in level of consciousness during sleep. Here we analysed …