IMI–Report on experimental models of emmetropization and myopia

D Troilo, EL Smith, DL Nickla, R Ashby… - … & visual science, 2019 - iovs.arvojournals.org
The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

[HTML][HTML] Dopamine signaling and myopia development: what are the key challenges

X Zhou, MT Pardue, PM Iuvone, J Qu - Progress in retinal and eye research, 2017 - Elsevier
In the face of an “epidemic” increase in myopia over the last decades and myopia
prevalence predicted to reach 2.5 billion people by the end of this decade, there is an urgent …

Myopia prevention and outdoor light intensity in a school-based cluster randomized trial

PC Wu, CT Chen, KK Lin, CC Sun, CN Kuo, HM Huang… - Ophthalmology, 2018 - Elsevier
Purpose To investigate the effectiveness of a school-based program promoting outdoor
activities in Taiwan for myopia prevention and to identify protective light intensities. Design …

Light and myopia: from epidemiological studies to neurobiological mechanisms

AR Muralidharan, C Lança, S Biswas… - Therapeutic …, 2021 - journals.sagepub.com
Myopia is far beyond its inconvenience and represents a true, highly prevalent, sight-
threatening ocular condition, especially in Asia. Without adequate interventions, the current …

Time outdoors and the prevention of myopia

AN French, RS Ashby, IG Morgan, KA Rose - Experimental eye research, 2013 - Elsevier
Recent epidemiological evidence suggests that children who spend more time outdoors are
less likely to be, or to become myopic, irrespective of how much near work they do, or …

An updated view on the role of dopamine in myopia

M Feldkaemper, F Schaeffel - Experimental eye research, 2013 - Elsevier
A large body of data is available to support the hypothesis that dopamine (DA) is one of the
retinal neurotransmitters involved in the signaling cascade that controls eye growth by …

A review of environmental risk factors for myopia during early life, childhood and adolescence

D Ramamurthy, SY Lin Chua… - Clinical and Experimental …, 2015 - Taylor & Francis
Myopia is a significant public health problem worldwide, particularly in East Asian countries.
The increasing prevalence of myopia poses a huge socio‐economic burden and …

Candidate pathways for retina to scleral signaling in refractive eye growth

DM Brown, R Mazade, D Clarkson-Townsend… - Experimental eye …, 2022 - Elsevier
The global prevalence of myopia, or nearsightedness, has increased at an alarming rate
over the last few decades. An eye is myopic if incoming light focuses prior to reaching the …

Animal models in myopia research

F Schaeffel, M Feldkaemper - Clinical and Experimental Optometry, 2015 - Taylor & Francis
Our current understanding of the development of refractive errors, in particular myopia,
would be substantially limited had Wiesel and Raviola not discovered by accident that …

Light signaling and myopia development: a review

P Zhang, H Zhu - Ophthalmology and Therapy, 2022 - Springer
Introduction The aim of this article was to comprehensively review the relationship between
light exposure and myopia with a focus on the effects of the light wavelength, illuminance …