The population doctrine in cognitive neuroscience

RB Ebitz, BY Hayden - Neuron, 2021 - cell.com
A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

Amygdala-cortical collaboration in reward learning and decision making

KM Wassum - Elife, 2022 - elifesciences.org
Adaptive reward-related decision making requires accurate prospective consideration of the
specific outcome of each option and its current desirability. These mental simulations are …

Foraging with the frontal cortex: a cross-species evaluation of reward-guided behavior

PH Rudebeck, A Izquierdo - Neuropsychopharmacology, 2022 - nature.com
Efficient foraging is essential to survival and depends on frontal cortex in mammals.
Because of its role in psychiatric disorders, frontal cortex and its contributions to reward …

A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories

AC Sias, AK Morse, S Wang, VY Greenfield… - Elife, 2021 - elifesciences.org
Adaptive reward-related decision making often requires accurate and detailed
representation of potential available rewards. Environmental reward-predictive stimuli can …

The rat frontal orienting field dynamically encodes value for economic decisions under risk

C Bao, X Zhu, J Mōller-Mara, J Li, S Dubroqua… - Nature …, 2023 - nature.com
Frontal and parietal cortex are implicated in economic decision-making, but their causal
roles are untested. Here we silenced the frontal orienting field (FOF) and posterior parietal …

Subpopulations of neurons in lOFC encode previous and current rewards at time of choice

DL Hocker, CD Brody, C Savin, CM Constantinople - Elife, 2021 - elifesciences.org
Studies of neural dynamics in lateral orbitofrontal cortex (lOFC) have shown that subsets of
neurons that encode distinct aspects of behavior, such as value, may project to common …

The orbitofrontal cartographer.

MPH Gardner, G Schoenbaum - Behavioral neuroscience, 2021 - psycnet.apa.org
Theories of orbitofrontal cortex (OFC) function have evolved substantially over the last few
decades. There is now a general consensus that the OFC is important for predicting aspects …

Value representations in the rodent orbitofrontal cortex drive learning, not choice

KJ Miller, MM Botvinick, CD Brody - Elife, 2022 - elifesciences.org
Humans and animals make predictions about the rewards they expect to receive in different
situations. In formal models of behavior, these predictions are known as value …

Is the core function of orbitofrontal cortex to signal values or make predictions?

J Zhou, MPH Gardner, G Schoenbaum - Current Opinion in Behavioral …, 2021 - Elsevier
One dominant hypothesis about the function of the orbitofrontal cortex (OFC) is that the OFC
signals the subjective values of possible outcomes to other brain areas for learning and …

Processing in lateral orbitofrontal cortex is required to estimate subjective preference during initial, but not established, economic choice

MPH Gardner, D Sanchez, JC Conroy, AM Wikenheiser… - Neuron, 2020 - cell.com
The orbitofrontal cortex (OFC) is proposed to be critical to economic decision making. Yet
one can inactivate OFC without affecting well-practiced choices. One possible explanation of …