Our understanding of how radiation kills normal and tumour cells has been based on an
intimate knowledge of the direct induction of DNA damage and its cellular consequences …

Evidence accumulated over the past two decades has indicated that exposure of cell
populations to ionizing radiation results in significant biological effects occurring in both the …

Significance: Radiation therapy (from external beams to unsealed and sealed radionuclide
sources) takes advantage of the detrimental effects of the clustered production of radicals …

The role of oxidative metabolism in the up-regulation/activation of stress-induciblesignaling
pathways as well as induction of micronucleus formation in bystander cells was investigated …

1-The main problem for both medical and non-medical uses of ionizing radiation is the
possible carcinogenic risks associated with small doses of ionizing radiation. These …

Background Auger electron emitters that can be targeted into DNA of tumour cells represent
an attractive systemic radiation therapy goal. In the situation of DNA-associated decay, the …

The term radiation-induced bystander effect is used to describe radiation-induced biological
changes that manifest in unirradiated cells remaining within an irradiated cell population …

For many years, targeted DNA damage caused by radiation has been considered the main
cause of various biological effects. Based on this paradigm, any small amount of radiation is …

Abstract Lyng, FM, Seymour, CB and Mothersill, C. Initiation of Apoptosis in Cells Exposed to
Medium from the Progeny of Irradiated Cells: A Possible Mechanism for Bystander-Induced …

Although radiation-induced bystander effects have been demonstrated in a number of cell
types, the studies have largely been performed using high linear energy transfer (LET) …