Apical–basal polarity and the control of epithelial form and function

CE Buckley, D St Johnston - Nature reviews Molecular cell biology, 2022 - nature.com
Epithelial cells are the most common cell type in all animals, forming the sheets and tubes
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …

Programmed and self-organized flow of information during morphogenesis

C Collinet, T Lecuit - Nature Reviews Molecular Cell Biology, 2021 - nature.com
How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

Adherens junctions as molecular regulators of emergent tissue mechanics

O Campàs, I Noordstra, AS Yap - Nature Reviews Molecular Cell …, 2024 - nature.com
Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors

SJ Streichan, MF Lefebvre, N Noll, EF Wieschaus… - Elife, 2018 - elifesciences.org
During embryogenesis tissue layers undergo morphogenetic flow rearranging and folding
into specific shapes. While developmental biology has identified key genes and local …

Harnessing mechanobiology for tissue engineering

S Kim, M Uroz, JL Bays, CS Chen - Developmental cell, 2021 - cell.com
A primary challenge in tissue engineering is to recapitulate both the structural and functional
features of whole tissues and organs. In vivo, patterning of the body plan and constituent …

Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms

L Zhao, F Gao, S Gao, Y Liang, H Long, Z Lv… - Science China Life …, 2021 - Springer
Evolutionary developmental biology, or Evo-Devo for short, has become an established field
that, broadly speaking, seeks to understand how changes in development drive major …

[HTML][HTML] Self-organized nuclear positioning synchronizes the cell cycle in Drosophila embryos

VE Deneke, A Puliafito, D Krueger, AV Narla… - Cell, 2019 - cell.com
The synchronous cleavage divisions of early embryogenesis require coordination of the cell-
cycle oscillator, the dynamics of the cytoskeleton, and the cytoplasm. Yet, it remains unclear …

Rigidity transitions in development and disease

E Hannezo, CP Heisenberg - Trends in Cell Biology, 2022 - cell.com
Although rigidity and jamming transitions have been widely studied in physics and material
science, their importance in a number of biological processes, including embryo …

Principles and applications of optogenetics in developmental biology

D Krueger, E Izquierdo, R Viswanathan… - …, 2019 - journals.biologists.com
The development of multicellular organisms is controlled by highly dynamic molecular and
cellular processes organized in spatially restricted patterns. Recent advances in …

Signaling dynamics control cell fate in the early Drosophila embryo

HE Johnson, JE Toettcher - Developmental cell, 2019 - cell.com
The Erk mitogen-activated protein kinase plays diverse roles in animal development. Its
widespread reuse raises a conundrum: when a single kinase like Erk is activated, how does …