Reactive oxygen‐dependent production of novel photochemotherapeutic agents
S PERVAIZ - The FASEB Journal, 2001 - Wiley Online Library
The reactive nature of species derived from oxygen, such as singlet oxygen and hydrogen
peroxide, has been exploited in the clinical setting for targeting bacteria, viruses, and tumor …
peroxide, has been exploited in the clinical setting for targeting bacteria, viruses, and tumor …
Morphological criteria to distinguish cell death induced by apoptotic and necrotic treatments
S Rello, JC Stockert, VL Moreno, A Gamez, M Pacheco… - Apoptosis, 2005 - Springer
We present a comparative study of apoptotic and necrotic morphology (light and scanning
electron microscopy), induced by well known experimental conditions (photodynamic …
electron microscopy), induced by well known experimental conditions (photodynamic …
Two combined photosensitizers: a goal for more effective photodynamic therapy of cancer
P Acedo, JC Stockert, M Cañete, A Villanueva - Cell death & disease, 2014 - nature.com
Photodynamic therapy (PDT) is a clinically approved therapeutic modality for the treatment
of diseases characterized by uncontrolled cell proliferation, mainly cancer. It involves the …
of diseases characterized by uncontrolled cell proliferation, mainly cancer. It involves the …
Characterization of the cell death modes and the associated changes in cellular energy supply in response to AlPcS4-PDT
K Plaetzer, T Kiesslich, B Krammer… - … & Photobiological Sciences, 2002 - Springer
Photodynamic therapy (PDT) can result in both types of cell death, apoptosis or necrosis.
Several steps in the induction and execution of apoptosis depend on ATP and the …
Several steps in the induction and execution of apoptosis depend on ATP and the …
Photodynamic activity of a new sensitizer derived from porphyrin-C60 dyad and its biological consequences in a human carcinoma cell line
MG Alvarez, C Prucca, ME Milanesio… - The international journal …, 2006 - Elsevier
The photokilling activity of a porphyrin-C60 (P-C60) dyad was evaluated on a Hep-2 human
larynx-carcinoma cell line. This study represents the first evaluation of a dyad, with high …
larynx-carcinoma cell line. This study represents the first evaluation of a dyad, with high …
Synthesis and photodynamic activity of zinc (II) phthalocyanine derivatives bearing methoxy and trifluoromethylbenzyloxy substituents in homogeneous and biological …
EI Yslas, V Rivarola, EN Durantini - Bioorganic & medicinal chemistry, 2005 - Elsevier
Two zinc (II) phthalocyanines bearing either four methoxy (ZnPc 3) or
trifluoromethylbenzyloxy (ZnPc 4) substituents have been synthesized by a two-step …
trifluoromethylbenzyloxy (ZnPc 4) substituents have been synthesized by a two-step …
Glycophthalocyanines as photosensitizers for triggering mitotic catastrophe and apoptosis in cancer cells
ARM Soares, MG Neves, AC Tome… - Chemical Research …, 2012 - ACS Publications
Photodynamic therapy (PDT) is a treatment modality for different forms of cancer based on
the combination of light, molecular oxygen, and a photosensitizer (PS) compound. When …
the combination of light, molecular oxygen, and a photosensitizer (PS) compound. When …
Zinc-(II) 2, 9, 16, 23-tetrakis (methoxy) phthalocyanine: Potential photosensitizer for use in photodynamic therapy in vitro
EI Yslas, EN Durantini, VA Rivarola - Bioorganic & medicinal chemistry, 2007 - Elsevier
Photodynamic therapy (PDT) is an innovative treatment for several types of malignant and
non-malignant disease. In the present study, ZnPcOCH3 was investigated on a human …
non-malignant disease. In the present study, ZnPcOCH3 was investigated on a human …
A new protocol in photodynamic therapy: enhanced tumour cell death by combining two different photosensitizers
A Villanueva, JC Stockert, M Cañete… - … & Photobiological Sciences, 2010 - Springer
The combined application of two photosensitisers (PSs), zinc (ii) phthalocyanine (ZnPc) and
the cationic porphyrin meso-tetrakis (4-N-methylpyridyl) porphine (T4MPyP), on HeLa cells …
the cationic porphyrin meso-tetrakis (4-N-methylpyridyl) porphine (T4MPyP), on HeLa cells …
Loss of E‐cadherin mediated cell–cell adhesion as an early trigger of apoptosis induced by photodynamic treatment
S Galaz, J Espada, JC Stockert… - Journal of cellular …, 2005 - Wiley Online Library
Photodynamic treatment with different photosensitizers (PSs) can result in the specific
induction of apoptosis in many cell types. It is commonly accepted that this apoptotic …
induction of apoptosis in many cell types. It is commonly accepted that this apoptotic …