Nucleus segmentation: towards automated solutions

R Hollandi, N Moshkov, L Paavolainen, E Tasnadi… - Trends in Cell …, 2022 - cell.com
Single nucleus segmentation is a frequent challenge of microscopy image processing, since
it is the first step of many quantitative data analysis pipelines. The quality of tracking single …

A survey on recent trends in deep learning for nucleus segmentation from histopathology images

A Basu, P Senapati, M Deb, R Rai, KG Dhal - Evolving Systems, 2024 - Springer
Nucleus segmentation is an imperative step in the qualitative study of imaging datasets,
considered as an intricate task in histopathology image analysis. Segmenting a nucleus is …

NuInsSeg: A fully annotated dataset for nuclei instance segmentation in H&E-stained histological images

A Mahbod, C Polak, K Feldmann, R Khan, K Gelles… - Scientific Data, 2024 - nature.com
In computational pathology, automatic nuclei instance segmentation plays an essential role
in whole slide image analysis. While many computerized approaches have been proposed …

ClusterSeg: A crowd cluster pinpointed nucleus segmentation framework with cross-modality datasets

J Ke, Y Lu, Y Shen, J Zhu, Y Zhou, J Huang, J Yao… - Medical Image …, 2023 - Elsevier
The detection and segmentation of individual cells or nuclei is often involved in image
analysis across a variety of biology and biomedical applications as an indispensable …

Evaluation of deep learning architectures for complex immunofluorescence nuclear image segmentation

F Kromp, L Fischer, E Bozsaky… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
Separating and labeling each nuclear instance (instance-aware segmentation) is the key
challenge in nuclear image segmentation. Deep Convolutional Neural Networks have been …

Ai system engineering—key challenges and lessons learned

L Fischer, L Ehrlinger, V Geist, R Ramler… - Machine Learning and …, 2020 - mdpi.com
The main challenges are discussed together with the lessons learned from past and
ongoing research along the development cycle of machine learning systems. This will be …

Microscopy analysis neural network to solve detection, enumeration and segmentation from image-level annotations

A Bilodeau, CVL Delmas, M Parent… - Nature Machine …, 2022 - nature.com
The development of deep learning approaches to detect, segment or classify structures of
interest has transformed the field of quantitative microscopy. High-throughput quantitative …

[HTML][HTML] Handcrafted Histological Transformer (H2T): Unsupervised representation of whole slide images

QD Vu, K Rajpoot, SEA Raza, N Rajpoot - Medical image analysis, 2023 - Elsevier
Diagnostic, prognostic and therapeutic decision-making of cancer in pathology clinics can
now be carried out based on analysis of multi-gigapixel tissue images, also known as whole …

Landscape of bone marrow metastasis in human neuroblastoma unraveled by transcriptomics and deep multiplex imaging

D Lazic, F Kromp, F Rifatbegovic, P Repiscak, M Kirr… - Cancers, 2021 - mdpi.com
Simple Summary Bone marrow metastasis frequently occurs in patients with solid cancers
and most often leads to poor outcome. Yet, the composition of bone marrow metastases …

Review of Disentanglement Approaches for Medical Applications--Towards Solving the Gordian Knot of Generative Models in Healthcare

J Fragemann, L Ardizzone, J Egger… - arXiv preprint arXiv …, 2022 - arxiv.org
Deep neural networks are commonly used for medical purposes such as image generation,
segmentation, or classification. Besides this, they are often criticized as black boxes as their …