Advances, Applications, and Perspectives in Small‐Angle X‐ray Scattering of RNA
JN Tants, A Schlundt - Chembiochem, 2023 - Wiley Online Library
RNAs exhibit a plethora of functions far beyond transmitting genetic information. Often, RNA
functions are entailed in their structure, be it as a regulatory switch, protein binding site, or …
functions are entailed in their structure, be it as a regulatory switch, protein binding site, or …
An overview of structural approaches to study therapeutic RNAs
L Mollica, FA Cupaioli, G Rossetti… - Frontiers in Molecular …, 2022 - frontiersin.org
RNAs provide considerable opportunities as therapeutic agent to expand the plethora of
classical therapeutic targets, from extracellular and surface proteins to intracellular nucleic …
classical therapeutic targets, from extracellular and surface proteins to intracellular nucleic …
Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains
SHP2 plays an important role in regulating cellular processes, and its pathogenic mutations
cause developmental disorders and are linked to cancer. SHP2 is a multidomain protein …
cause developmental disorders and are linked to cancer. SHP2 is a multidomain protein …
[HTML][HTML] The Drosophila RNA binding protein Hrp48 binds a specific RNA sequence of the msl-2 mRNA 3'UTR to regulate translation
A Lomoschitz, J Meyer, T Guitart, M Krepl… - Biophysical …, 2025 - Elsevier
Repression of msl-2 mRNA translation is essential for viability of Drosophila melanogaster
females to prevent hypertranscription of both X chromosomes. This translational control …
females to prevent hypertranscription of both X chromosomes. This translational control …
Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26
A Salerno-Kochan, A Horn, P Ghosh… - Life Science …, 2022 - life-science-alliance.org
The TRIM-NHL protein Meiotic P26 (Mei-P26) acts as a regulator of cell fate in Drosophila.
Its activity is critical for ovarian germline stem cell maintenance, differentiation of oocytes …
Its activity is critical for ovarian germline stem cell maintenance, differentiation of oocytes …