[HTML][HTML] Dendritic cells and macrophages in the pathogenesis of psoriasis

M Kamata, Y Tada - Frontiers in immunology, 2022 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
This disease impairs patients' quality of life enormously. Pathological findings demonstrate …

[HTML][HTML] Psoriatic arthritis: pathogenesis and targeted therapies

AB Azuaga, J Ramírez, JD Cañete - International journal of molecular …, 2023 - mdpi.com
Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease
characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and …

Reactive oxygen species-responsive gel-based microneedle patches for prolonged and intelligent psoriasis management

D Bi, F Qu, W Xiao, J Wu, P Liu, H Du, Y Xie, H Liu… - ACS …, 2023 - ACS Publications
Psoriasis is an inflammatory skin disease. Microneedle (MN) patches can improve psoriasis
treatment outcomes by increasing local drug content in the skin. As psoriasis frequently …

The holistic approach to psoriasis patients with comorbidities: the role of investigational drugs

E Camela, L Potestio, G Fabbrocini… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Psoriasis is a high-burden syndrome characterized by cutaneous and
extracutaneous manifestations that profoundly reduce patients' quality of life. The presence …

[HTML][HTML] Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Updated perspectives on keratinocytes and psoriasis: keratinocytes are more than innocent bystanders

LI Ortiz-Lopez, V Choudhary… - Psoriasis: Targets and …, 2022 - Taylor & Francis
Psoriasis is a complex disease triggered by genetic, immunologic, and environmental
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …

[HTML][HTML] Comprehensive insight into lichen planus immunopathogenesis

M Vičić, N Hlača, M Kaštelan, I Brajac… - International Journal of …, 2023 - mdpi.com
Lichen planus is a chronic disease affecting the skin, appendages, and mucous
membranes. A cutaneous lichen planus is a rare disease occurring in less than 1% of the …

[HTML][HTML] Vitamin D signaling in psoriasis: pathogenesis and therapy

AA Brożyna, RM Slominski, B Nedoszytko… - International Journal of …, 2022 - mdpi.com
Psoriasis is a systemic, chronic, immune-mediated disease that affects approximately 2–3%
of the world's population. The etiology and pathophysiology of psoriasis are still unknown …

[HTML][HTML] TRPV1: a promising therapeutic target for skin aging and inflammatory skin diseases

T Xiao, M Sun, C Zhao, J Kang - Frontiers in pharmacology, 2023 - frontiersin.org
TRPV1 is a non-selective channel receptor widely expressed in skin tissues, including
keratinocytes, peripheral sensory nerve fibers and immune cells. It is activated by a variety of …

The skin microbiome and its role in psoriasis: a review

V Celoria, F Rosset, V Pala, P Dapavo… - … : Targets and Therapy, 2023 - Taylor & Francis
The skin microbiome is made of various microorganisms, most of which have the function of
protecting individuals from harmful pathogens, and they are involved in innate and adaptive …