Neuroimmunological diseases and their treatment compromise the immune system, thereby increasing the risk of infections and serious illness. Consequently, vaccinations to protect …
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2 remain asymptomatic,,–. Although most global efforts have focused on severe illness in …
Multisystem inflammatory syndrome in children (MIS-C) is a severe, post-infectious sequela of SARS-CoV-2 infection,, yet the pathophysiological mechanism connecting the infection to …
Z Pang, A Tang, Y He, J Fan, Q Yang… - Clinical Microbiology …, 2024 - journals.asm.org
SUMMARY SARS-CoV-2 can not only cause respiratory symptoms but also lead to neurological complications. Research has shown that more than 30% of SARS-CoV-2 …
Abstract Introduction Responses to SARS‐CoV‐2 vaccination in patients with MS (pwMS) varies by disease‐modifying therapies (DMTs). We perform a meta‐analysis and systematic …
D Dixit, VM Hallisey, EYS Zhu… - The Journal of …, 2024 - Am Soc Clin Investig
Effective immunity requires a large, diverse naive T cell repertoire circulating among lymphoid organs in search of antigen. Sphingosine 1-phosphate (S1P) and its receptor …
AT Reder, O Stuve, SK Tankou… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Background: Multiple sclerosis (MS) is a neurological disorder marked by accumulating immune-mediated damage to the central nervous system. The dysregulated immune system …
I Kister, Y Patskovsky, R Curtin, J Pei… - Annals of …, 2022 - Wiley Online Library
Objective The objective of this study was to determine the impact of multiple sclerosis (MS) disease‐modifying therapies (DMTs) on the development of cellular and humoral immunity …
Background Adequate response to the SARS-CoV-2 vaccine represents an important treatment goal in caring for patients with multiple sclerosis (MS) during the ongoing COVID …