The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a
century. It has also generated considerable biomedical interest not only because of its …

Hypoxia is one of the strongest environmental drivers of cellular and physiological
adaptation. Although most mammals are largely intolerant of hypoxia, some specialized …

Migratory flight requires birds to maintain intensive aerobic exercise for many hours or days.
Maintaining O2 supply to flight muscles is therefore important during migration, especially …

Reactive oxygen species (ROS) are important cellular signalling molecules but sudden
changes in redox balance can be deleterious to cells and lethal to the whole organism. ROS …

The naked mole-rat of the family Bathyergidae has been the showpiece for ageing research
as they contradict the traditional understanding of the oxidative stress theory of ageing …

The doubly labeled water (DLW) technique and indirect calorimetry enable measurement of
an animal's daily energy expenditure (DEE, kJ/day), resting metabolic rate (RMR, kJ/d) …

Hypoxia poses a major physiological challenge for mammals and has significant impacts on
cellular and systemic metabolism. As with many other small rodents, naked mole-rats …

The effect of the macro-and microclimate on small mammal thermoregulation in the past has
been studied independently instead of investigating the dual effect of both the components …

Mammals have evolved circadian rhythms in internal biological processes and behaviors,
such as locomotor activity (LA), to synchronize to the environmental conditions they …

Naked mole-rats (NMRs) are among the most hypoxia-tolerant mammals and metabolize
only carbohydrates in hypoxia. Glucose is the primary building block of dietary …