Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …

Guanine-rich DNA and RNA sequences can fold into noncanonical nucleic acid structures
called G-quadruplexes (G4s). Since the discovery that these structures may act as scaffolds …

Common fragile sites (CFSs) are genomic regions that are unstable under conditions of
replicative stress. Although the characteristics of CFSs that render them vulnerable to stress …

Genome-wide studies of DNA replication origins revealed that origins preferentially
associate with an Origin G-rich Repeated Element (OGRE), potentially forming G …

Viruses are the most abundant organisms on our planet, affecting all living beings: some of
them are responsible for massive epidemics that concern health, national economies and …

G-quadruplexes are non-canonical nucleic-acid structures that control transcription,
replication, and recombination in organisms. G-quadruplexes are present in eukaryotes …

G-quadruplex is a special secondary structure of nucleic acids in guanine-rich sequences of
genome. G-quadruplexes have been proved to be involved in the regulation of replication …

G-quadruplex (or G4) structures form in guanine-rich DNA sequences and threaten genome
stability when not properly resolved. G4 unwinding occurs during S phase via an unknown …

A G-quadruplex (G4) is a four-stranded nucleic acid secondary structure maintained by
Hoogsteen hydrogen bonds established between four guanines. Experimental studies and …

G-quadruplexes (G4s) are noncanonical nucleic acid secondary structures formed by
guanine-rich DNA and RNA sequences. In this review we aim to provide an overview of the …