A comparative study of variables influencing ischemic injury in the Longa and Koizumi methods of intraluminal filament middle cerebral artery occlusion in mice
The intraluminal filament model of middle cerebral artery occlusion (MCAO) in mice and rats
has been plagued by inconsistency, owing in part to the multitude of variables requiring …
has been plagued by inconsistency, owing in part to the multitude of variables requiring …
MRI guiding of the middle cerebral artery occlusion in rats aimed to improve stroke modeling
IL Gubskiy, DD Namestnikova, EA Cherkashova… - Translational stroke …, 2018 - Springer
The middle cerebral artery occlusion (MCAO) model in rats closely imitates ischemic stroke
and is widely used. Existing instrumental methods provide a certain level of MCAO …
and is widely used. Existing instrumental methods provide a certain level of MCAO …
Neuroprotective effect of lercanidipine in middle cerebral artery occlusion model of stroke in rats
S Gupta, U Sharma, NR Jagannathan, YK Gupta - Experimental neurology, 2017 - Elsevier
Oxidative stress, inflammation and apoptotic neuronal cell death are cardinal mechanisms
involved in the cascade of acute ischemic stroke. Lercanidipine apart from calcium channel …
involved in the cascade of acute ischemic stroke. Lercanidipine apart from calcium channel …
Protective effects of Chrysin against memory impairment, cerebral hyperemia and oxidative stress after cerebral hypoperfusion and reperfusion in rats
Stroke is devastating and a leading cause of morbidity and mortality worldwide. Cerebral
ischemia-reperfusion and its subsequent reactive hyperemia lead to neuronal damage in …
ischemia-reperfusion and its subsequent reactive hyperemia lead to neuronal damage in …
Hemodynamics and tissue Optical Properties in Bimodal Infarctions Induced by Middle cerebral artery occlusion
Various infarct sizes induced by middle cerebral artery occlusion (MCAO) generate
inconsistent outcomes for stroke preclinical study. Monitoring cerebral hemodynamics may …
inconsistent outcomes for stroke preclinical study. Monitoring cerebral hemodynamics may …
Phosphodiesterase 10A is a critical target for neuroprotection in a mouse model of ischemic stroke
Abstract Phosphodiesterase 10A (PDE10A) hydrolyzes adenosine 3′, 5′-cyclic
monophosphate (cAMP) and guanosine 3′, 5′-cyclic monophosphate (cGMP). It is highly …
monophosphate (cAMP) and guanosine 3′, 5′-cyclic monophosphate (cGMP). It is highly …
A murine model of ischemic retinal injury induced by transient bilateral common carotid artery occlusion
Diverse vascular diseases such as diabetic retinopathy, occlusion of retinal veins or arteries
and ocular ischemic syndrome can lead to retinal ischemia. To investigate pathological …
and ocular ischemic syndrome can lead to retinal ischemia. To investigate pathological …
Toward accurate cerebral blood flow estimation in mice after accounting for anesthesia
Purpose: To improve the accuracy of cerebral blood flow (CBF) measurement in mice by
accounting for the anesthesia effects. Methods: The dependence of CBF on anesthesia dose …
accounting for the anesthesia effects. Methods: The dependence of CBF on anesthesia dose …
[HTML][HTML] Induction of ischemic stroke and ischemia-reperfusion in mice using the middle artery occlusion technique and visualization of infarct area
L Bertrand, L Dygert, M Toborek - Journal of Visualized …, 2017 - pmc.ncbi.nlm.nih.gov
Cerebrovascular disease is highly prevalent in the global population and encompasses
several types of conditions, including stroke. To study the impact of stroke on tissue injury …
several types of conditions, including stroke. To study the impact of stroke on tissue injury …
Small separation diffuse correlation spectroscopy for measurement of cerebral blood flow in rodents
E Sathialingam, SY Lee, B Sanders, J Park… - Biomedical optics …, 2018 - opg.optica.org
Diffuse correlation spectroscopy (DCS) has shown promise as a means to non-invasively
measure cerebral blood flow in small animal models. Here, we characterize the validity of …
measure cerebral blood flow in small animal models. Here, we characterize the validity of …