New and emerging approaches to treat psychiatric disorders
Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …
the lives of millions of people worldwide. Although their etiological and diagnostic …
[HTML][HTML] Inflammation-related functional and structural dysconnectivity as a pathway to psychopathology
Findings from numerous laboratories and across neuroimaging modalities have consistently
shown that exogenous administration of cytokines or inflammatory stimuli that induce …
shown that exogenous administration of cytokines or inflammatory stimuli that induce …
[HTML][HTML] How inflammation affects the brain in depression: a review of functional and structural MRI studies
This narrative review discusses how peripheral and central inflammation processes affect
brain function and structure in depression, and reports on recent peripheral inflammatory …
brain function and structure in depression, and reports on recent peripheral inflammatory …
[HTML][HTML] Early social adversity, altered brain functional connectivity, and mental health
Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …
factors for the onset of severe mental disorders and strong and consistent predictors of …
[HTML][HTML] Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine …
Increased inflammation in major depressive disorder (MDD) has been associated with low
functional connectivity (FC) in corticostriatal reward circuits and symptoms of anhedonia …
functional connectivity (FC) in corticostriatal reward circuits and symptoms of anhedonia …
Stress to inflammation and anhedonia: Mechanistic insights from preclinical and clinical models
Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward
motivation, and/or deficits in reward-related learning, is a common feature of depression …
motivation, and/or deficits in reward-related learning, is a common feature of depression …
Inflammation‐driven brain and gut barrier dysfunction in stress and mood disorders
Regulation of emotions is generally associated exclusively with the brain. However, there is
evidence that peripheral systems are also involved in mood, stress vulnerability vs …
evidence that peripheral systems are also involved in mood, stress vulnerability vs …
Presentation and management of anxiety in individuals with acute symptomatic or asymptomatic COVID-19 infection, and in the post-COVID-19 recovery phase
G Uzunova, S Pallanti, E Hollander - International journal of …, 2021 - Taylor & Francis
COVID-19 is associated with neuropsychiatric complications, the most frequent one being
anxiety. Multiple biological and psychosocial factors contribute to anxiety in COVID-19 …
anxiety. Multiple biological and psychosocial factors contribute to anxiety in COVID-19 …
Aiding and abetting anhedonia: impact of inflammation on the brain and pharmacological implications
Exogenous administration of inflammatory stimuli to humans and laboratory animals and
chronic endogenous inflammatory states lead to motivational deficits and ultimately …
chronic endogenous inflammatory states lead to motivational deficits and ultimately …
[HTML][HTML] Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression
Objective There is increasing evidence for a subgroup of major depressive disorder (MDD)
associated with heightened peripheral blood inflammatory markers. In this study, we aimed …
associated with heightened peripheral blood inflammatory markers. In this study, we aimed …