Medical advances and the availability of diagnostic tools have considerably increased life
expectancy and, consequently, the elderly segment of the world population. As age is a …

Growing evidence has demonstrated exercise as an effective way to promote cardiovascular
health and protect against cardiovascular diseases However, the underlying mechanisms of …

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are
pivotal regulators of extracellular matrix (ECM) composition and could, due to their dynamic …

Clinical trials have shown that sodium glucose co-transporter 2 (SGLT2) inhibitors improve
clinical outcomes in diabetes mellitus (DM) patients. As most studies were performed in …

The treatment of hypertensive patients with losartan is very common. Despite the reduction
in blood pressure, its effects on cardiac contractility and sympathetic autonomic drive are still …

Although current guidelines recommend resistance exercise in combination with aerobic
training to increase muscle strength and prevent skeletal muscle loss during cardiac …

Although the morphological features and functions of adipose tissue are well-described in
obesity-prone animal models, less information is available on animals such as the stroke …

Aim To evaluate the influence of physical training on myocardial function, oxidative stress,
energy metabolism, and MAPKs and NF-κB signaling pathways in spontaneously …

Aim To evaluate the influence of high-intensity interval training (HIIT) on cardiac structural
and functional characteristics and myocardial mitogen-activated protein kinase (MAPK) …

Purpose: In this study, we investigated the effect of treadmill exercise training on cardiac
hypertrophy, collagen deposition, echo parameters and serum levels of cardiac troponin I …