What is known about breast cancer in young women?

JW Zhu, P Charkhchi, S Adekunte, MR Akbari - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is the most common cancer affecting women under 40 years
of age worldwide, with an increasing number of cases diagnosed each year. Despite this …

Pregnancy after breast cancer: a systematic review and meta-analysis

M Lambertini, E Blondeaux, M Bruzzone… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Many patients and physicians remain concerned about the potential detrimental
effects of pregnancy after breast cancer (BC) in terms of reproductive outcomes and …

A review of modifiable risk factors in young women for the prevention of breast cancer

AA Daly, R Rolph, RI Cutress… - Breast Cancer: Targets …, 2021 - Taylor & Francis
Breast cancer is the most common cancer diagnosis in women aged less than 40 years and
the second most common cause of cancer death in this age group. Global rates of young …

[HTML][HTML] Moderate penetrance genes complicate genetic testing for breast cancer diagnosis: ATM, CHEK2, BARD1 and RAD51D

R Graffeo, HQ Rana, F Conforti, B Bonanni… - The Breast, 2022 - Elsevier
Breast cancer risk associated with germline likely pathogenic/pathogenic variants (PV)
varies by gene, often by penetrance (high> 50% or moderate 20–50%), and specific locus …

Pregnancy After Breast Cancer in Patients With Germline BRCA Mutations

M Lambertini, L Ameye, AS Hamy… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Young women with germline BRCA mutations have unique reproductive
challenges. Pregnancy after breast cancer does not increase the risk of recurrence; …

[HTML][HTML] ESO–ESMO fifth international consensus guidelines for breast cancer in young women (BCY5)

S Paluch-Shimon, F Cardoso, AH Partridge… - Annals of …, 2022 - Elsevier
Highlights•Breast cancer in young women encompasses unique treatment and survivorship
considerations.•Fertility, ovarian function suppression and premature menopause are major …

Immunotherapy in triple-negative breast cancer: Insights into tumor immune landscape and therapeutic opportunities

R Ribeiro, MJ Carvalho, J Goncalves… - Frontiers in Molecular …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer that
represents 15–20% of breast tumors and is more prevalent in young pre-menopausal …

[HTML][HTML] Who are the women who enrolled in the POSITIVE trial: a global study to support young hormone receptor positive breast cancer survivors desiring pregnancy

AH Partridge, SM Niman, M Ruggeri, FA Peccatori… - The Breast, 2021 - Elsevier
Background Premenopausal women with early hormone-receptor positive (HR+) breast
cancer receive 5–10 years of adjuvant endocrine therapy (ET) during which pregnancy is …

[HTML][HTML] Treatment of breast cancer in young adults

ME Tesch, AH Partridge - American Society of Clinical Oncology …, 2022 - ascopubs.org
Although breast cancer is rare and understudied in adults age 40 and younger, recent
epidemiologic data show an increasing incidence of breast cancer among young women in …

Update on the management of breast cancer during pregnancy

F Poggio, M Tagliamento, C Pirrone, D Soldato… - Cancers, 2020 - mdpi.com
Simple Summary The diagnosis of cancer during pregnancy represents a challenging
situation, leading to a complex management aimed at maximizing the curative approach to …