Drug repurposing for cancer therapy

Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …

Procyanidin B2: A promising multi-functional food-derived pigment for human diseases

J Chen, K Zhong, Y Jing, S Liu, S Qin, F Peng, D Li… - Food Chemistry, 2023 - Elsevier
Natural edible pigments play a paramount part in the food industry. Procyanidin B2 (PB2),
one of the most representative naturally occurring edible pigments, is usually isolated from …

[HTML][HTML] Revolutionizing mushroom processing: Innovative techniques and technologies

S Sangeeta, D Sharma, S Ramniwas, R Mugabi… - Food Chemistry: X, 2024 - Elsevier
In recent years, the global mushroom industry has seen remarkable growth due to its
nutritional benefits, increasing market value, and rising consumer demand. Mushrooms are …

[HTML][HTML] Optimizing CRISPR/Cas9 precision: Mitigating off-target effects for safe integration with photodynamic and stem cell therapies in cancer treatment

JPJ Merlin, H Abrahamse - Biomedicine & Pharmacotherapy, 2024 - Elsevier
CRISPR/Cas9 precision genome editing has revolutionized cancer treatment by introducing
specific alterations to the cancer genome. But the therapeutic potential of CRISPR/Cas9 is …

Anticancer perspectives of genistein: a comprehensive review

H Naeem, U Momal, M Imran, M Shahbaz… - … Journal of Food …, 2023 - Taylor & Francis
There is a significant load of degenerative and chronic illnesses, especially cancer, which is
one of the main reasons for morbidity and death globally. Polyphenolic phytochemicals …

[HTML][HTML] Combining Photodynamic Therapy and Targeted Drug Delivery Systems: Enhancing Mitochondrial Toxicity for Improved Cancer Outcomes

JPJ Merlin, A Crous, H Abrahamse - International journal of molecular …, 2024 - mdpi.com
Cancer treatment continues to be a substantial problem due to tumor complexities and
persistence, demanding novel therapeutic techniques. This review investigates the …

Nano‐phototherapy: Favorable prospects for cancer treatment

JPJ Merlin, A Crous… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Nanotechnology‐based phototherapies have drawn interest in the fight against cancer
because of its noninvasiveness, high flexibility, and precision in terms of cancer targeting …

Effects of in vitro fecal fermentation on the metabolism and antioxidant properties of cyanidin-3-O-glucoside

B Wang, X Tang, B Mao, Q Zhang, F Tian, J Zhao… - Food Chemistry, 2024 - Elsevier
Anthocyanins' potential health benefits have garnered significant interest. However, due to
low bioavailability, the gut microbiota-associated metabolites are suspected to mediate their …

Advancing Photodynamic Therapy with Nano-Conjugated Hypocrellin: Mechanisms and Clinical Applications

SS Rajan, R Chandran… - International Journal of …, 2024 - Taylor & Francis
Hypocrellin-based photodynamic therapy (PDT) is developing as a viable cancer
therapeutic option, especially when enhanced by nanoconjugation. This review investigates …

Alleviates effects of γ-cyclodextrin/genistein inclusion complex on oxidative stress injury induced by organic hydrogen peroxide in PC12 cells via Nrf2/GPx4 signaling …

M Zhang, J Liu, Y Yu, W Ren, R Yuan, X Liu, X Shang… - Food Bioscience, 2025 - Elsevier
Genistein (GEN) is the most abundant aglycone in soy isoflavones and is a key factor
distinguishing soybeans from other food sources. It holds significant nutritional value and …