Diabetic Nephropathy (DN) is a serious complication of type I and II diabetes. It develops
from the initial microproteinuria to end-stage renal failure. The main initiator for DN is chronic …

The catabolic process that delivers cytoplasmic constituents to the lysosome for degradation,
known as autophagy, is thought to act as a cytoprotective mechanism in response to stress …

Both autophagy and podocyte epithelial-mesenchymal transition (EMT) are critical factors in
glomerular diseases that involve proteinuria and fibrosis. Here, we sought to determine …

Insufficient autophagy in podocytes is related to podocyte injury in diabetic nephropathy
(DN). Advanced glycation end‐products (AGEs) are major factors of podocyte injury in DN …

Atherosclerosis (AS) is a chronic inflammatory disease involving blood vessels.
Inflammation affects different cells and increases the expression of adhesion molecules …

Aim Mesangial cell (MC) activation plays an important role in many glomerular diseases
associated with renal fibrosis, including diabetic kidney disease (DKD). The aim of this study …

Melatonin (MLT) is a biologically active indoleamine involved in regulating various
biological rhythms, which is deficient in individuals with Type 2 diabetes. The present study …

OBJECTIVE: Evidence suggested that deficiency of autophagy is involved in the
pathogenesis of diabetic nephropathy (DN). However, some recent studies have also shown …

Skin aging is a complex process and involves extrinsic and intrinsic processes with distinct
characteristics. Understanding skin aging requires knowledge of the senescence of human …

Background. Podocyte injury plays an important role in diabetic nephropathy (DN). The aim
of this study was to determine the potential therapeutic effects of the ginsenoside Rg1 on …