Continuous Flow Upgrading of Selected C2–C6 Platform Chemicals Derived from Biomass

R Gerardy, DP Debecker, J Estager, P Luis… - Chemical …, 2020 - ACS Publications
The ever increasing industrial production of commodity and specialty chemicals inexorably
depletes the finite primary fossil resources available on Earth. The forecast of population …

The Green ChemisTREE: 20 years after taking root with the 12 principles

HC Erythropel, JB Zimmerman, TM de Winter… - Green chemistry, 2018 - pubs.rsc.org
The field of Green Chemistry has seen many scientific discoveries and inventions during the
20 years since the 12 Principles were first published. Inspired by tree diagrams that illustrate …

A perspective on continuous flow chemistry in the pharmaceutical industry

M Baumann, TS Moody, M Smyth… - … Process Research & …, 2020 - ACS Publications
Continuous flow manufacture is an innovative technology platform, which is gaining
momentum within the pharmaceutical industry. The key advantages of continuous flow …

Review on the current practices and efforts towards pilot-scale production of metal-organic frameworks (MOFs)

J Ren, X Dyosiba, NM Musyoka, HW Langmi… - Coordination Chemistry …, 2017 - Elsevier
Metal-organic frameworks (MOFs) have been under development over the past 20 years.
Similar to other technologies, research on MOFs in the upcoming 30 years will move …

The medicinal chemistry in the era of machines and automation: recent advances in continuous flow technology

A Gioiello, A Piccinno, AM Lozza… - Journal of medicinal …, 2020 - ACS Publications
Medicinal chemistry plays a fundamental and underlying role in chemical biology,
pharmacology, and medicine to discover safe and efficacious drugs. Small molecule …

The molecular industrial revolution: automated synthesis of small molecules

M Trobe, MD Burke - Angewandte Chemie International Edition, 2018 - Wiley Online Library
Today we are poised for a transition from the highly customized crafting of specific molecular
targets by hand to the increasingly general and automated assembly of different types of …

Flow biocatalysis: A challenging alternative for the synthesis of APIs and natural compounds

M Santi, L Sancineto, V Nascimento… - International journal of …, 2021 - mdpi.com
Biocatalysts represent an efficient, highly selective and greener alternative to metal catalysts
in both industry and academia. In the last two decades, the interest in biocatalytic …

Polymer synthesis in continuous flow reactors

N Zaquen, M Rubens, N Corrigan, J Xu… - Progress in Polymer …, 2020 - Elsevier
A variety of polymerizations has long been performed in continuous flow reactors on an
industrial scale; comparatively, on smaller scales, continuous polymerization methods have …

Continuous flow organic chemistry: successes and pitfalls at the interface with current societal challenges

R Gérardy, N Emmanuel, T Toupy… - European Journal of …, 2018 - Wiley Online Library
This review intends to provide the reader with a clear and concise overview of how
preparative continuous flow organic chemistry could potentially impact on current important …

Analytical tools integrated in continuous-flow reactors: which one for what?

M Rodriguez-Zubiri, FX Felpin - Organic Process Research & …, 2022 - ACS Publications
The concept and practices of chemical synthesis are being profoundly transformed toward
the development of fully autonomous continuous processes. Critical to the development of …