The roles and mechanisms of coding and noncoding RNA variations in cancer

SY Kim, MJ Na, S Yoon, E Shin, JW Ha… - … & Molecular Medicine, 2024 - nature.com
Functional variations in coding and noncoding RNAs are crucial in tumorigenesis, with
cancer-specific alterations often resulting from chemical modifications and …

The functions and mechanisms of piRNAs in mediating mammalian spermatogenesis and their applications in reproductive medicine

L Du, W Chen, D Zhang, Y Cui, Z He - Cellular and Molecular Life …, 2024 - Springer
As the most abundant small RNAs, piwi-interacting RNAs (piRNAs) have been identified as
a new class of non-coding RNAs with 24–32 nucleotides in length, and they are expressed …

LncRNAway: a web-based sgRNA design tool for precise and effective suppression of long noncoding RNAs

S Zhang, S Wang, F Lu, L Bie, Y Luo, J Sun… - Nucleic Acids …, 2024 - academic.oup.com
Thousands of long noncoding RNAs (lncRNAs) have been annotated via high-throughput
RNA sequencing, yet only a small fraction have been functionally investigated. Genomic …

[HTML][HTML] Crosstalk between Long Non-Coding RNA and Spliceosomal microRNA as a Novel Biomarker for Cancer

M Arafat, R Sperling - Non-coding RNA, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) play diverse roles in regulating cellular processes and have
been implicated in pathological conditions, including cancer, where interactions between …

miRNAs as Interconnectors between Obesity and Cancer

GD González-Sánchez, AJ Granados-López… - Non-coding RNA, 2024 - mdpi.com
Obesity and cancer are a concern of global interest. It is proven that obesity may trigger the
development or progression of some types of cancer; however, the connection by non …

An intricate rewiring of cancer metabolism via alternative splicing

G Temaj, S Chichiarelli, S Saha… - Biochemical …, 2023 - Elsevier
All human genes undergo alternative splicing leading to the diversity of the proteins.
However, in some cases, abnormal regulation of alternative splicing can result in diseases …

Brucella abortus triggers the differential expression of immunomodulatory lncRNAs in infected murine macrophages

M Flores-Concha, LA Gomez, R Soto-Shara… - Frontiers in …, 2024 - frontiersin.org
Introduction The lncRNAs (long non-coding RNAs) are the most diverse group of non-coding
RNAs and are involved in most biological processes including the immune response. While …

RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer

X Xie, HP Macknight, AL Lu, CE Chalfant - Molecular Therapy Nucleic Acids, 2025 - cell.com
The CDKN2A gene, responsible for encoding the tumor suppressors p16 (INK4A) and p14
(ARF), is frequently inactivated in non-small cell lung cancer (NSCLC). Herein, an …

Target mimicry: The interplay of LncRNAs and MiRNAs in the complex network of abiotic stress responses in Oryza sativa

R Rakhi, PS Kohli, NB Alam, N Yadav, A Jain… - Environmental and …, 2024 - Elsevier
Initially dismissed as 'junk DNA', genomic progress highlights the essential role of non-
coding regulatory RNAs (ncRNAs) in gene expression. Long non-coding RNA (lncRNAs) …

Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell …

SS Zhao, DL Tao, JM Chen, MY Zhang… - Microbiology …, 2024 - journals.asm.org
Neospora caninum is one of the most common pathogens causing reproductive failure in
ruminants (eg, cattle and goats) worldwide. However, due to a poor understanding of the …