Engineered cardiac tissues

RK Iyer, LLY Chiu, LA Reis, M Radisic - Current opinion in biotechnology, 2011 - Elsevier
Cardiac tissue engineering offers the promise of creating functional tissue replacements for
use in the failing heart or for in vitro drug screening. The last decade has seen a great deal …

Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells

N Cao, Z Liu, Z Chen, J Wang, T Chen, X Zhao, Y Ma… - Cell research, 2012 - nature.com
Generation of induced pluripotent stem cells (iPSCs) has opened new avenues for the
investigation of heart diseases, drug screening and potential autologous cardiac …

[PDF][PDF] Cardiac tissue engineering: current state and perspectives

LL Chiu, RK Iyer, LA Reis, SS Nunes, M Radisic - Front Biosci, 2012 - article.imrpress.com
[Frontiers in Bioscience 17, 1533-1550, January 1, 2012] 1533 Cardiac tissue engineering:
current state and perspectives Loraine Page 1 [Frontiers in Bioscience 17, 1533-1550 …

A Novel Miniaturized Multimodal Bioreactor for Continuous In Situ Assessment of Bioartificial Cardiac Tissue During Stimulation and Maturation

G Kensah, I Gruh, J Viering, H Schumann… - … Engineering Part C …, 2011 - liebertpub.com
Stem cell-based cardiac tissue engineering is a promising approach for regenerative
therapy of the injured heart. At present, the small number of stem cell-derived …

Development of gelatin/ascorbic acid cryogels for potential use in corneal stromal tissue engineering

LJ Luo, JY Lai, SF Chou, YJ Hsueh, DHK Ma - Acta biomaterialia, 2018 - Elsevier
To offer an ideal hospitable environment for corneal keratocyte growth, the carrier materials
can be functionalized with incorporation of signaling molecules to regulate cell biological …

An autologous platelet-rich plasma hydrogel compound restores left ventricular structure, function and ameliorates adverse remodeling in a minimally invasive large …

TD Vu, SN Pal, LK Ti, EC Martinez, AJ Rufaihah… - Biomaterials, 2015 - Elsevier
Aims Cell-based myocardial restoration has not penetrated broad clinical practice yet due to
poor cell retention and survival rates. In this study, we attempt a translational, large-scale …

Generation of bioartificial heart tissue by combining a three-dimensional gel-based cardiac construct with decellularized small intestinal submucosa

Z Vukadinovic-Nikolic, B Andrée… - … Engineering Part A, 2014 - liebertpub.com
The in vitro generation of a bioartificial cardiac construct (CC) represents a promising tool for
the repair of ischemic heart tissue. Several approaches to engineer cardiac tissue in vitro …

Cord lining-mesenchymal stem cells graft supplemented with an omental flap induces myocardial revascularization and ameliorates cardiac dysfunction in a rat model …

S Lilyanna, EC Martinez, TD Vu, LH Ling… - … Engineering Part A, 2013 - liebertpub.com
Myocardial restoration using tissue-engineered grafts to regenerate the ischemic
myocardium offers improved donor cell retention, yet a limited cell survival resulting from …

Priming with ligands secreted by human stromal progenitor cells promotes grafts of cardiac stem/progenitor cells after myocardial infarction

Y Iso, KS Rao, CN Poole, AKMT Zaman, I Curril… - Stem Cells, 2014 - academic.oup.com
Transplantation of culture-expanded adult stem/progenitor cells often results in poor cellular
engraftment, survival, and migration into sites of tissue injury. Mesenchymal cells including …

Metabolic alteration of HepG2 in scaffold‐based 3‐D culture: Proteomic approach

D Pruksakorn, K Lirdprapamongkol… - …, 2010 - Wiley Online Library
D cell culture models are important in cancer biology since they provide improved
understanding of tumor microenvironment. We have established a 3‐D culture model using …