[HTML][HTML] Recent advances in lean NAFLD

R Xu, J Pan, W Zhou, G Ji, Y Dang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
As the predominant type of chronic liver disease, the growing prevalence of nonalcoholic
fatty liver disease (NAFLD) has become a concern worldwide. Although obesity plays the …

Circulating histones to detect and monitor the progression of cancer

DK Tsoneva, MN Ivanov, NV Conev, R Manev… - International journal of …, 2023 - mdpi.com
Liquid biopsies have emerged as a minimally invasive cancer detection and monitoring
method, which could identify cancer-related alterations in nucleosome or histone levels and …

Lean or diabetic subtypes predict increased all-cause and disease-specific mortality in metabolic-associated fatty liver disease

GE Chung, SJ Yu, JJ Yoo, Y Cho, K Lee, DW Shin… - BMC medicine, 2023 - Springer
Background Metabolic-associated fatty liver disease (MAFLD) encompasses diverse
disease groups with potentially heterogeneous clinical outcomes. We investigated the risk of …

Liquid biopsy in hepatocellular carcinoma: where are we now?

F Pelizzaro, R Cardin, B Penzo, E Pinto, A Vitale… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the mostly lethal cancers, with a
prognosis which is still very poor. Novel reliable biomarkers, useful in early diagnosis and …

An update in epigenetics in metabolic-associated fatty liver disease

JS Rodríguez-Sanabria, R Escutia-Gutiérrez… - Frontiers in …, 2022 - frontiersin.org
Metabolic-associated fatty liver disease (MAFLD) is characterized by hepatic steatosis
accompanied by one of three features: overweight or obesity, T2DM, or lean or normal …

Exposure to bedroom light pollution and cardiometabolic risk: a cohort study from Chinese young adults

Y Xu, Y Yu, Y Huang, Y Wan, P Su, F Tao, Y Sun - Environmental Pollution, 2022 - Elsevier
Indoor light environment has altered dramatically and exposure to light at night (LAN)
potential leads to the progression of cardiometabolic conditions. However, few studies have …

Genetic and epigenetic determinants of non-alcoholic fatty liver disease (NAFLD) in lean individuals: a systematic review

B Njei, YA Al-Ajlouni, D Ugwendum… - Translational …, 2023 - pmc.ncbi.nlm.nih.gov
Background Non-alcoholic fatty liver disease (NAFLD) is common in obese individuals, but
its occurrence in lean individuals and the underlying mechanisms are not well understood …

Epigenetic regulation in lean nonalcoholic fatty liver disease

I Aggeletopoulou, M Kalafateli, EP Tsounis… - International Journal of …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), the most prominent cause of chronic liver disease
worldwide, is a rapidly growing epidemic. It consists of a wide range of liver diseases, from …

Epigenetic biomarkers for the diagnosis and treatment of liver disease

M Arechederra, M Recalde, M Gárate-Rascón… - Cancers, 2021 - mdpi.com
Simple Summary Cellular identity and function depends on the correct and specific
expression of genetic information. Different epigenetic mechanisms including DNA …

Prospective study of the association between chronotype and cardiometabolic risk among Chinese young adults

T Li, Y Xie, S Tao, L Zou, Y Yang, F Tao, X Wu - BMC Public Health, 2023 - Springer
Background The association of evening chronotype with cardiometabolic disease has been
well established. However, the extent to which circadian rhythm disturbances independently …