Dual inhibition of MAPK/ERK and BMP signaling induces entorhinal-like identity in mouse ESC-derived pallial progenitors

F Tonelli, L Iannello, S Gustincich, A Di Garbo… - Stem Cell Reports, 2025 - cell.com
The mechanisms that determine distinct embryonic pallial identities remain elusive. The
central role of Wnt signaling in directing dorsal telencephalic progenitors to the isocortex or …

Differentiation state and culture conditions impact neural stem/progenitor cell-derived extracellular vesicle bioactivity

D Dutta, NH Pirolli, D Levy, J Tsao, N Seecharan… - Biomaterials …, 2023 - pubs.rsc.org
Extracellular vesicles (EVs) derived from neural progenitor/stem cells (NPSCs) have shown
promising efficacy in a variety of preclinical models. However, NPSCs lack critical …

A renaissance for developmental biology driven by new in vitro platforms

JM Wells - Development, 2022 - journals.biologists.com
Over the past 30 years, I have routinely told my students that this is the most exciting time in
history to be a developmental biologist. This has been especially true over the last decade …