Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

Filamentous fungi are harnessed as cell factories for the production of a diverse range of
organic acids, proteins, and secondary metabolites. Growth and morphology have critical …

Filamentous fungi are a large and ancient clade of microorganisms that occupy a broad
range of ecological niches. The success of filamentous fungi is largely due to their elongate …

Pathogens utilize a panoply of effectors to manipulate plant defense. However, despite their
importance, relatively little is actually known about regulation of these virulence factors …

The exocyst is a hetero-octameric complex that has been proposed to serve as the tethering
complex for exocytosis, although it remains poorly understood at the molecular level. Here …

Exocytosis involves the fusion of intracellular secretory vesicles with the plasma membrane,
thereby delivering integral membrane proteins to the cell surface and releasing material into …

Highlights•The Spitzenkörper (SPK) is a highly ordered structure of hyphal apices.•The SPK
determines hyphal growth and morphogenesis.•Neurospora crassa provides insight into the …

A major challenge for a molecular understanding of membrane trafficking has been the
elucidation of high-resolution structures of large, multisubunit tethering complexes that …

Magnaporthe oryzae is the causal agent of rice blast disease, the most devastating disease
of cultivated rice (Oryza sativa) and a continuing threat to global food security. To cause …

The filamentous ascomycete fungus Aspergillus niger is a prolific secretor of organic acids,
proteins, enzymes and secondary metabolites. Throughout the last century, biotechnologists …