Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across
the globe at unprecedented speed and is showing no signs of slowing down. The outbreak …

Background and Purpose—Stroke mortality has been declining since the early 20th century.
The reasons for this are not completely understood, although the decline is welcome. As a …

Obesity is at epidemic proportions in the United States and in other developed and
developing countries. The prevalence of obesity is increasing not only in adults, but …

Background Obesity is associated with increased mortality. Weight loss improves
cardiovascular risk factors, but no prospective interventional studies have reported whether …

Background Obesity, defined by a body-mass index (BMI)(the weight in kilograms divided by
the square of the height in meters) of 30.0 or more, is associated with an increased risk of …

ContextThe association of body mass index (BMI) with cause-specific mortality has not been
reported for the US population. ObjectiveTo estimate cause-specific excess deaths …

Background The extent to which moderate overweight (body mass index [BMI], 25.0-29.9
[calculated as weight in kilograms divided by height in meters squared]) and obesity (BMI,≥ …

Insulin-mediated glucose disposal varies at least sixfold in apparently healthy individuals.
The adverse effect of decreases in the level of physical fitness on insulin sensitivity is …

Background and objectives: Obesity is an independent risk factor for development and
progression of chronic kidney disease (CKD). We conducted a systematic review to assess …

Methods An extensive electronic search was conducted in MEDLINE (1966–January 2009),
EMBASE (1988–January 2009), the Cochrane Library (1990–January 2009), and Web of …