Chronic inflammation has been associated with an increased risk of several human
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …

Helicobacter pylori infection is a well-established risk factor for the development of gastric
cancer (GC). Understanding the immunopathogenesis underlying this association is crucial …

Background Conflicting results of recent studies on the association between Helicobacter
pylori (H. pylori) infection and the risk of insulin resistance and metabolic syndrome explored …

Innate immunity represents the first barrier against bacterial invasion. Toll‐like receptors
(TLRs) belong to the large family of pattern recognition receptors (PRRs), and their …

Growing studies revealed the association between polymorphisms in Toll-like receptor 4
(TLR4) and susceptibility to cancer, however, the results remained inconsistent. To assess …

Gastric cancer (GC) is the fifth most common cancer and the fourth most common cause of
cancer-related death worldwide. The intestinal type of GC progresses from acute to chronic …

Helicobacter pylori colonizes the gastric mucosa of more than 50% of the human population,
causing chronic inflammation, which however is largely asymptomatic. Nevertheless, H …

Background In addition to Helicobacter pylori infection, host genetic factors contribute to
gastric cancer (GC). Recognition of H. pylori is known to involve Toll-like receptors (TLR) …

Background Gastric cancer (GC) is a progressive process initiated by Helicobacter pylori-
induced inflammation. Initial recognition of H. pylori involves Toll-like receptors (TLRs) …

Background and aims MicroRNAs (miRNAs) are known for their function as translational
regulators of tumor suppressor or oncogenes. Single nucleotide polymorphisms (SNPs) in …