Immunogenicity of extracellular vesicles

Y Xia, J Zhang, G Liu, J Wolfram - Advanced Materials, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …

Therapeutic and pharmacological applications of extracellular vesicles and lipoproteins

K Németh, BM Kestecher, S Ghosal… - British Journal of …, 2024 - Wiley Online Library
In recent years, various approaches have been undertaken to eliminate lipoproteins co‐
isolated with extracellular vesicles, as they were initially regarded as contaminating entities …

Nanomaterials: leading immunogenic cell death-based cancer therapies

C Ma, Z Cheng, H Tan, Y Wang, S Sun… - Frontiers in …, 2024 - frontiersin.org
The field of oncology has transformed in recent years, with treatments shifting from
traditional surgical resection and radiation therapy to more diverse and customized …

Extracellular vesicle gatekeepers for tumours

J Wolfram - Nature Materials, 2024 - nature.com
Extracellular vesicle gatekeepers for tumours | Nature Materials Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Intercellular crosstalk between cancer cells and cancer-associated fibroblasts via exosomes in gastrointestinal tumors

L Cao, H Ouyang - Frontiers in Oncology, 2024 - frontiersin.org
Gastrointestinal (GI) tumors are a significant global health threat, with high rates of morbidity
and mortality. Exosomes contain various biologically active molecules like nucleic acids …

Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Precision Medicine

A Sharma, A Yadav, A Nandy, S Ghatak - Pharmaceutics, 2024 - mdpi.com
Of all the numerous nanosized extracellular vesicles released by a cell, the endosomal-
originated exosomes are increasingly recognized as potential therapeutics, owing to their …

Increasing the biomolecular relevance of cell culture practice

RE Ghebosu, L Hui, J Wolfram - Journal of Biomedical Science, 2025 - Springer
The biomolecular relevance of medium supplements is a key challenge affecting cell culture
practice. The biomolecular composition of commonly used supplements differs from that of a …

[HTML][HTML] A bibliometric analysis of extracellular vesicles as drug delivery vehicles in disease treatment (2010–2024)

W Guo, Q Shu, L Gao, N Gao, Z Wang, W Wei… - Extracellular …, 2024 - Elsevier
To comprehensively summarize the progress of utilizing extracellular vesicles (EVs) as drug
delivery vehicles in disease treatment, bibliometric and visualization tools were employed to …

[HTML][HTML] Reduced Intra-and Extracellular Circulating Postprandial Lysosomal Acid Lipase Activity in Patients with MASLD

M Mischitelli, E Poggiogalle, G Tozzi, F Ferri, S Parisse… - Metabolites, 2024 - mdpi.com
Background/Objectives: Low fasting blood lysosomal acid lipase (LAL) activity is associated
with the pathogenesis of metabolic hepatic steatosis. We measured LAL activity in blood and …

Attempts to preserve and visualize protein corona on the surface of biological nanoparticles in blood serum using photomodification

JE Poletaeva, AV Tupitsyna… - Beilstein Journal of …, 2024 - beilstein-journals.org
A protein corona is present on any nanoparticle (NP) entering biological fluids; however, the
existence of a natural protein corona on natural NPs has not been experimentally confirmed …