Pharmacological potentials of lycopene against aging and aging‐related disorders: A review

MH Abir, AGMSU Mahamud, SH Tonny… - Food Science & …, 2023 - Wiley Online Library
Aging and aging‐related chronic disorders are one of the principal causes of death
worldwide. The prevalence of these disorders is increasing gradually and globally …

Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum …

M Ileriturk, O Kandemir, N Akaras, H Simsek… - Reproductive …, 2023 - Elsevier
Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side
effects. Hesperidin (HES) has a wide range of biological and pharmacological properties …

[HTML][HTML] The potential roles of ATF family in the treatment of Alzheimer's disease

T Yang, Y Zhang, L Chen, ER Thomas, W Yu… - Biomedicine & …, 2023 - Elsevier
Activating transcription factors, ATFs, is a family of transcription factors that activate gene
expression and transcription by recognizing and combining the cAMP response element …

Lycopene alleviates di (2-ethylhexyl) phthalate-induced splenic injury by activating P62-Keap1-NRF2 signaling

XY Dai, SY Zhu, J Chen, MZ Li, Y Zhao… - Food and Chemical …, 2022 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is an omnipresent environmental pollutant. It
has been determined that DEHP is involved in multiple health disorders. Lycopene (Lyc) is a …

Investigation of the effects of hesperidin administration on abamectin‐induced testicular toxicity in rats through oxidative stress, endoplasmic reticulum stress …

C Gur, O Kandemir, FM Kandemir - Environmental Toxicology, 2022 - Wiley Online Library
In this study, the potential effects of hesperidin (HES) on chronic toxicity caused by
abamectin (ABM) in the testicular tissue were investigated through oxidative stress …

Evaluation of protective effects of quercetin against cypermethrin‐induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and …

M Ileriturk, O Kandemir… - Environmental …, 2022 - Wiley Online Library
Cypermethrin (CYP), a type II synthetic pyrethroid, is the most widely used insecticide
worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential …

Rutin protects rat liver and kidney from sodium valproate-induce damage by attenuating oxidative stress, ER stress, inflammation, apoptosis and autophagy

FM Kandemir, M Ileriturk, C Gur - Molecular biology reports, 2022 - Springer
Background The present study investigated the effects of rutin (RUT), which has various
biological and pharmacological properties, on liver and kidney damage caused by histone …

Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating …

A Yardim, FM Kandemir, S Ozdemir, S Kucukler… - Neurotoxicology, 2020 - Elsevier
In the present study, the protective effects of quercetin on peripheral neurotoxicity caused by
vincristine, which is used effectively in the treatment of various types of cancers, were …

The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats

HS Semis, FM Kandemir, O Kaynar, T Dogan… - Life Sciences, 2021 - Elsevier
Paclitaxel (PTX), which is widely used in the treatment of solid tumors, leads to dose
limitation because it causes peripheral neuropathy. This study was conducted to evaluate …

Evaluation of therapeutic effects of quercetin against Achilles tendinopathy in rats via oxidative stress, inflammation, apoptosis, autophagy, and metalloproteinases

HS Semis, C Gur, M Ileriturk… - … American journal of …, 2022 - journals.sagepub.com
Background: Achilles tendinopathy, seen in athletes and manual labor workers, is an
inflammatory condition characterized by chronic tendon pain. Owing to the toxicity that …