[HTML][HTML] The evolving role of diagnostic genomics in kidney transplantation
J Soraru, A Chakera, N Isbel… - Kidney International …, 2022 - Elsevier
Monogenic forms of heritable kidney disease account for a significant proportion of chronic
kidney disease (CKD) across both pediatric and adult patient populations and up to 11% of …
kidney disease (CKD) across both pediatric and adult patient populations and up to 11% of …
Impact of the MIF -173G/C variant on cardiovascular disease risk: a meta-analysis of 9,047 participants
Introduction Many factors contribute to the risk of cardiovascular disease (CVD), an umbrella
term for several different heart diseases, including inflammation. Macrophage migration …
term for several different heart diseases, including inflammation. Macrophage migration …
Interleukin Variants Are Associated with the Development and Progression of IgA Nephropathy: A Candidate-Gene Association Study and Meta-Analysis
I Chronopoulou, M Tziastoudi, G Pissas… - International Journal of …, 2023 - mdpi.com
The interleukin-1 gene cluster encodes cytokines, which modulate mesangial cell
proliferation and matrix expansion, both constituting central factors in the development and …
proliferation and matrix expansion, both constituting central factors in the development and …
Inappropriate prescribing in patients with kidney disease: A rapid review of prevalence, associated clinical outcomes and impact of interventions
Z Hamzaei, MB Houlind, LJ Kjeldsen… - Basic & clinical …, 2024 - Wiley Online Library
Background The prevalence of patients with chronic kidney disease (CKD) and
polypharmacy is increasing and has amplified the importance of examining inappropriate …
polypharmacy is increasing and has amplified the importance of examining inappropriate …
ABCB1 gene polymorphisms impact the effect of high‐dose intravenous methylprednisolone therapy on optic neuritis associated with AQP4‐IgG‐positive …
Y Dai, S Ni, F Wu, S Guo, X Zhao… - Journal of Clinical …, 2022 - Wiley Online Library
Abstract What Is Known and Objective Patients with optic neuritis (ON) have significant
individual differences in their response to high‐dose intravenous methylprednisolone …
individual differences in their response to high‐dose intravenous methylprednisolone …
[HTML][HTML] Navigating Genetic Testing in Nephrology: Options and Decision-Making Strategies
E Groopman, HM Rasouly - Kidney International Reports, 2024 - Elsevier
Technological advances such as next-generation sequencing (NGS) have enabled high-
throughput assessment of the human genome, supporting the usage of genetic testing as a …
throughput assessment of the human genome, supporting the usage of genetic testing as a …
Selective Fluorescent Probes for High-Throughput Functional Diagnostics of the Human Multidrug Transporter P-Glycoprotein (ABCB1)
E Szabó, A Kulin, B Jezsó, N Kucsma… - International Journal of …, 2022 - mdpi.com
The multidrug transporter ABCB1 (MDR1, Pgp) plays an important role in the absorption,
distribution, metabolism, and elimination of a wide range of pharmaceutical compounds …
distribution, metabolism, and elimination of a wide range of pharmaceutical compounds …
Analysis of Pharmacogenomic Very Important Pharmacogenomic Variants: CYP3A5, ACE, PTGS2 and NAT2 Genes in Chinese Bai Population
W Meng, W Zhang, S Yang, X Dou, Y Liu, H Li… - Personalized …, 2022 - Taylor & Francis
Aim: Our study aimed to screen the genotype frequencies of very important
pharmacogenomic (VIP) mutations and identify their differences between Bai and other …
pharmacogenomic (VIP) mutations and identify their differences between Bai and other …
Immune-Related Gene Polymorphisms and Pharmacogenetic Studies in Nephrology
ABSTRACT A large subgroup of patients with chronic kidney disease still encounter serious
adverse effects and lack of responsiveness to medications, possibly because of the …
adverse effects and lack of responsiveness to medications, possibly because of the …