DA Lewinsohn, DM Lewinsohn, TJ Scriba - Frontiers in immunology, 2017 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of morbidity and mortality worldwide, despite the widespread use of the only licensed vaccine …
R Tanner, B Villarreal-Ramos… - Frontiers in …, 2019 - frontiersin.org
Bacillus Calmette Guérin (BCG) is the only currently available vaccine against tuberculosis (TB), but it confers incomplete and variable protection against pulmonary TB in humans and …
BCG turns 100 this year and while it might not be the perfect vaccine, it has certainly contributed significantly towards eradication and prevention of spread of tuberculosis (TB) …
AJ Jacobs, J Mongkolsapaya, GR Screaton… - Tuberculosis, 2016 - Elsevier
Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine …
J Lange, O Rivera-Ballesteros, M Buggert - Mucosal immunology, 2022 - Elsevier
Memory T cells are fundamental to maintain immune surveillance of the human body. During the past decade, it has become apparent that non-recirculating resident memory T cells …
P Ogongo, JZ Porterfield, A Leslie - Frontiers in immunology, 2019 - frontiersin.org
Despite widespread BCG vaccination and effective anti-TB drugs, Tuberculosis (TB) remains the leading cause of death from an infectious agent worldwide. Several recent publications …
Background There is an urgent need for an effective tuberculosis (TB) vaccine. Heterologous prime–boost regimens induce potent cellular immunity. MVA85A is a …
S Sharpe, A White, C Sarfas, L Sibley, F Gleeson… - Tuberculosis, 2016 - Elsevier
Intradermal (ID) BCG injection provides incomplete protection against TB in humans and experimental models. Alternative BCG vaccination strategies may improve protection in …
L Shen, J Frencher, D Huang… - Proceedings of the …, 2019 - National Acad Sciences
Tuberculosis (TB) remains a leading killer among infectious diseases, and a better TB vaccine is urgently needed. The critical components and mechanisms of vaccine-induced …