Recent advances on chitosan as an adjuvant for vaccine delivery
I Dmour, N Islam - International Journal of Biological Macromolecules, 2022 - Elsevier
Chitosan (CS) is a natural polymer derived from chitin that has wide applications in drugs,
vaccines, and antigen delivery. The distinctive mucoadhesive, biocompatibility …
vaccines, and antigen delivery. The distinctive mucoadhesive, biocompatibility …
Polyfunctional CD4+ T Cells As Targets for Tuberculosis Vaccination
DA Lewinsohn, DM Lewinsohn, TJ Scriba - Frontiers in immunology, 2017 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of
morbidity and mortality worldwide, despite the widespread use of the only licensed vaccine …
morbidity and mortality worldwide, despite the widespread use of the only licensed vaccine …
The humoral immune response to BCG vaccination
R Tanner, B Villarreal-Ramos… - Frontiers in …, 2019 - frontiersin.org
Bacillus Calmette Guérin (BCG) is the only currently available vaccine against tuberculosis
(TB), but it confers incomplete and variable protection against pulmonary TB in humans and …
(TB), but it confers incomplete and variable protection against pulmonary TB in humans and …
A century of BCG: Impact on tuberculosis control and beyond
BCG turns 100 this year and while it might not be the perfect vaccine, it has certainly
contributed significantly towards eradication and prevention of spread of tuberculosis (TB) …
contributed significantly towards eradication and prevention of spread of tuberculosis (TB) …
[HTML][HTML] Antibodies and tuberculosis
AJ Jacobs, J Mongkolsapaya, GR Screaton… - Tuberculosis, 2016 - Elsevier
Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million
new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine …
new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine …
[HTML][HTML] Human mucosal tissue-resident memory T cells in health and disease
Memory T cells are fundamental to maintain immune surveillance of the human body. During
the past decade, it has become apparent that non-recirculating resident memory T cells …
the past decade, it has become apparent that non-recirculating resident memory T cells …
Lung Tissue Resident Memory T-Cells in the Immune Response to Mycobacterium tuberculosis
Despite widespread BCG vaccination and effective anti-TB drugs, Tuberculosis (TB) remains
the leading cause of death from an infectious agent worldwide. Several recent publications …
the leading cause of death from an infectious agent worldwide. Several recent publications …
Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial
ZR Manjaly Thomas, I Satti, JL Marshall… - PLoS …, 2019 - journals.plos.org
Background There is an urgent need for an effective tuberculosis (TB) vaccine.
Heterologous prime–boost regimens induce potent cellular immunity. MVA85A is a …
Heterologous prime–boost regimens induce potent cellular immunity. MVA85A is a …
[HTML][HTML] Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: protection associated with mycobacterial …
Intradermal (ID) BCG injection provides incomplete protection against TB in humans and
experimental models. Alternative BCG vaccination strategies may improve protection in …
experimental models. Alternative BCG vaccination strategies may improve protection in …
Immunization of Vγ2Vδ2 T cells programs sustained effector memory responses that control tuberculosis in nonhuman primates
L Shen, J Frencher, D Huang… - Proceedings of the …, 2019 - National Acad Sciences
Tuberculosis (TB) remains a leading killer among infectious diseases, and a better TB
vaccine is urgently needed. The critical components and mechanisms of vaccine-induced …
vaccine is urgently needed. The critical components and mechanisms of vaccine-induced …