The microbiome-shaping roles of bacteriocins

S Heilbronner, B Krismer, H Brötz-Oesterhelt… - Nature Reviews …, 2021 - nature.com
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

Coagulase-negative staphylococci pathogenomics

X Argemi, Y Hansmann, K Prola, G Prévost - International journal of …, 2019 - mdpi.com
Coagulase-negative Staphylococci (CoNS) are skin commensal bacteria. Besides their role
in maintaining homeostasis, CoNS have emerged as major pathogens in nosocomial …

Staphylococcal-Produced Bacteriocins and Antimicrobial Peptides: Their Potential as Alternative Treatments for Staphylococcus aureus Infections

LL Newstead, K Varjonen, T Nuttall, GK Paterson - Antibiotics, 2020 - mdpi.com
Staphylococcus aureus is an important pathogen of both humans and animals, implicated in
a wide range of infections. The emergence of antibiotic resistance has resulted in S. aureus …

High throughput in situ metagenomic measurement of bacterial replication at ultra-low sequencing coverage

A Emiola, J Oh - Nature communications, 2018 - nature.com
Abstract We developed Growth Rate InDex (GRiD) for estimating in situ growth rates of ultra-
low coverage (> 0.2×) and de novo-assembled metagenomes. Applying GRiD to human and …

Nisin J, a novel natural nisin variant, is produced by Staphylococcus capitis sourced from the human skin microbiota

JN O'Sullivan, PM O'Connor, MC Rea… - Journal of …, 2020 - Am Soc Microbiol
The skin microbiota is thought to play a key role in host protection from infection. Nisin J is a
novel nisin variant produced by Staphylococcus capitis APC 2923, a strain isolated from the …

Staphylococcus capitis: Review of Its Role in Infections and Outbreaks

V Heath, E Cloutman-Green, S Watkin, M Karlikowska… - Antibiotics, 2023 - mdpi.com
In June 2021, a national incident team was formed due to an increased detection of
Staphylococcus capitis in samples from hospitalised infants. Staphylococcus capitis has …

Staphylococcus aureus Colonization of the Human Nose and Interaction with Other Microbiome Members

C Laux, A Peschel, B Krismer - Microbiology Spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is usually regarded as a bacterial pathogen due to its ability to
cause multiple types of invasive infections. Nevertheless, S. aureus colonizes about 30% of …

[HTML][HTML] Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes

AM O'Neill, T Nakatsuji, A Hayachi, MR Williams… - Journal of Investigative …, 2020 - Elsevier
The microbiome represents a vast resource for drug discovery, as its members engage in
constant conflict to outcompete one another by deploying diverse strategies for survival …

The dynamic balance of the skin microbiome across the lifespan

EC Townsend, LR Kalan - Biochemical Society Transactions, 2023 - portlandpress.com
For decades research has centered on identifying the ideal balanced skin microbiome that
prevents disease and on developing therapeutics to foster this balance. However, this single …

Bacteriocin-like inhibitory substances in staphylococci of different origins and species with activity against relevant pathogens

R Fernández-Fernández, C Lozano… - Frontiers in …, 2022 - frontiersin.org
Bacteriocins are antimicrobial peptides with relevance in the modulation of human and
animal microbiota that have gained interest in biomedical and biotechnological applications …