Inflammation, structural, and functional abnormalities within the airways are key features of
asthma. Although these processes are well documented, their expression varies across the …

Galectins are a family of animal lectins with diverse biological activities. They function both
extracellularly, by interacting with cell-surface and extracellular matrix glycoproteins and …

Galectins, an ancient lectin family, are characterized by specific binding of β-galactosides
through evolutionary conserved sequence elements of carbohydrate-recognition domain …

Galectins are a family of animal lectins that bind β-galactosides. Outside the cell, galectins
bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular …

Galectins, β‐galactoside‐binding animal lectins, are differentially expressed by various
immune cells as well as a wide range of other cell types. Extracellularly, galectins are able to …

Galectins are a family of mammalian β-galactoside-binding proteins that positively and
negatively regulate T cell death. Extracellular galectin-1 directly induces death of T cells and …

Recent evidence has implicated galectins and their ligands as master regulators of immune
cell homeostasis. Whereas some members of this family, such as galectin-3, behave as …

We have explored the fundamental biological processes by which complex carbohydrates
expressed on cellular glycoproteins and glycolipids and in secretions of cells promote cell …

The glycocalyx is a glycan layer found on the surfaces of host cells as well as
microorganisms and enveloped virus. Its thickness may easily exceed 50 nm. The …

Galectin-3 (gal-3) is a β-galactoside-binding lectin, which regulates cell–cell and
extracellular interactions during self/non-self-antigen recognition and cellular activation …