Platelet activation is a complex balance of positive and negative signaling pathways. The
protein kinase C (PKC) family is a major regulator of platelet granule secretion, integrin …

The rapid secretion of bioactive amines from chromaffin cells constitutes an important
component of the fight or flight response of mammals to stress. Platelets respond to stresses …

Platelets are specialized adhesive cells that play a key role in normal and pathological
hemostasis through their ability to rapidly adhere to subendothelial matrix proteins (platelet …

The myristoylated alanine-rich C-kinase substrate (MARCKS) protein has been at the
crossroads of multiple signaling pathways that govern several critical operations in normal …

BACKGROUND: A major characteristic of asthmatic airways is an increase in mucin (the
glycoprotein component of mucus) producing and secreting cells, which leads to increased …

MARCKS (myristoylated alanine-rich C kinase substrate) is a prominent PKC substrate
expressed in all eukaryotic cells. It is known to bind to and cross-link actin filaments, to serve …

Myristoylated alanine-rich C kinase substrate (MARCKS), an acidic, heat-stable protein, is
involved in important physiological functions such as neurotransmitter release and re …

Taurolithocholate (TLC) acutely inhibits the biliary excretion of multidrug‐resistant
associated protein 2 (Mrp2) substrates by inducing Mrp2 retrieval from the canalicular …

Infection with group B streptococcus (GBS) is the most common cause of early onset
neonatal sepsis in many countries, leading to neonatal morbidity and mortality. There is …

Myristoylated alanine-rich protein kinase C substrate (MARCKS) is a cellular substrate for
protein kinase C (PKC). Recently, we have shown that PKC isoforms-α and-δ, as well as the …