Calcium phosphate composite layers for surface-mediated gene transfer
In this review, the surface-mediated gene transfer system using calcium phosphate
composite layers is described. Calcium phosphate ceramics are osteoconductive …
composite layers is described. Calcium phosphate ceramics are osteoconductive …
Bio-functional inorganic materials: an attractive branch of gene-based nano-medicine delivery for 21st century
EH Chowdhury, T Akaike - Current gene therapy, 2005 - ingentaconnect.com
Treatment of a physiological disorder in the genetic level (gene therapy) and induction of a
specific immunity by means of a genetic material (genetic vaccination), are considered two …
specific immunity by means of a genetic material (genetic vaccination), are considered two …
Controlled superficial assembly of DNA–amorphous calcium phosphate nanocomposite spheres for surface-mediated gene delivery
A Oyane, H Araki, M Nakamura, Y Shimizu… - Colloids and Surfaces B …, 2016 - Elsevier
Surface-mediated gene delivery systems have many potential applications in tissue
engineering. We recently fabricated an assembly consisting of DNA–amorphous calcium …
engineering. We recently fabricated an assembly consisting of DNA–amorphous calcium …
Control of gene transfer on a DNA–fibronectin–apatite composite layer by the incorporation of carbonate and fluoride ions
Gene transfer techniques are useful tools for controlling cell behavior, such as proliferation
and differentiation. We have recently developed an efficient area-specific gene transfer …
and differentiation. We have recently developed an efficient area-specific gene transfer …
Fibronectin‐DNA‐apatite composite layer for highly efficient and area‐specific gene transfer
A Oyane, M Murayama, A Yamazaki… - … Research Part A: An …, 2010 - Wiley Online Library
In 2004, Shen et al. developed a safe and efficient gene transfer system using a DNA-apatite
composite layer. We have recently succeeded in improving further the gene transfer …
composite layer. We have recently succeeded in improving further the gene transfer …
[HTML][HTML] pH-responsive magnesium-and carbonate-substituted apatite nano-crystals for efficient and cell-targeted delivery of transgenes
EH Chowdhury - 2013 - scirp.org
The short half-lives due to the enzymatic degradation in blood, the lack of tissue targetability
and the incapability to passively diffuse across the plasma membrane and smoothly traffic …
and the incapability to passively diffuse across the plasma membrane and smoothly traffic …
Optimization of transfection mediated by calcium phosphate for plasmid rAAV‐LacZ (recombinant adeno‐associated virus–β‐galactosidase reporter gene) production …
L Feng, M Guo, S Zhang, J Chu… - Biotechnology and …, 2007 - Wiley Online Library
rAAV (recombinant adeno‐associated virus) has become a very useful gene‐delivery vector
for gene therapy. However, it is very difficult to generate rAAV using triple transfection on a …
for gene therapy. However, it is very difficult to generate rAAV using triple transfection on a …
Fabrication of a DNA-lipid-apatite composite layer for efficient and area-specific gene transfer
A surface-mediated gene transfer system using biocompatible apatite-based composite
layers has great potential for tissue engineering. Among the apatite-based composite layers …
layers has great potential for tissue engineering. Among the apatite-based composite layers …
Small addition of Zn 2+ in Ca 2+@ DNA results in elevated gene transfection by aminated PGMA-modified silicon nanowire arrays
Gene therapy, a promising and effective treatment, has ignited new hope in overcoming
difficult-to-cure diseases. The key question in gene therapy is how to efficiently and safely …
difficult-to-cure diseases. The key question in gene therapy is how to efficiently and safely …
Coprecipitation of DNA-lipid complexes with apatite and comparison with superficial adsorption for gene transfer applications
Y Yazaki, A Oyane, H Tsurushima… - Journal of …, 2014 - journals.sagepub.com
Apatite can mediate gene transfer into cells by serving as a safe and biocompatible
immobilization matrix for DNA and transfection reagents. Recently, an apatite layer that …
immobilization matrix for DNA and transfection reagents. Recently, an apatite layer that …