BACKGROUND: This systematic review has two purposes: to consolidate the current
knowledge about clinical effectiveness of electrochemotherapy, a highly effective local …

Photodynamic therapy (PDT) is a cancer treatment modality that is based on the
administration of a photosensitiser, which is retained in tumour tissues more than in normal …

A new concept in the therapy of both neoplastic and non-neoplastic diseases is discussed in
this article. Photodynamic therapy (PDT) involves light activation, in the presence of …

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues
is one of the most challenging areas in medicine, a wide range of optical techniques has …

Various types of optical spectroscopy have been investigated as methods to effect a
noninvasive, real-time in-situ assessment of tissue pathology. All of these methods have one …

The novel ability to quantify drug and tracer concentrations in vivo by optical means leads to
the possibility of detecting and quantifying blood brain barrier (BBB) disruption in real-time …

We have investigated the possibility of determining the optical coefficients of muscle in the
extremities with in vivo time-resolved reflectance measurements using a layered model. A …

Rapid first pass uptake of drugs is necessary to increase tissue deposition after intraarterial
(IA) injection. Here we tested whether brain tissue deposition of a nanoparticulate liposomal …

A reflectance spectroscopic device that utilizes a single fiber for both light delivery and
collection has advantages over classical multi-fiber probes. This study presents a novel …

We developed a real-time drug-reporting conjugate (CPT-SS-CyN) composed of a near-
infrared (NIR) fluorescent cyanine-amine dye (CyN), a disulfide linker, and a model …