Neuroinflammation has become a key hallmark of neurological complications including
perioperative pathologies such as postoperative delirium and longer-lasting postoperative …

Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which
seriously threatens the quality of patients' life, especially the older people. Accumulating …

For half a century, we have known that some patients experience neurocognitive dysfunction
after cardiac surgery, yet defining its incidence, course, and causes remains challenging …

Degeneration of central cholinergic neurons impairs memory, and enhancement of
cholinergic synapses improves cognitive processes. Cholinergic signaling is also anti …

Sevoflurane is one of the most widely used anesthetics for the induction and maintenance of
general anesthesia in surgical patients. Sevoflurane treatment may increase the incidence …

Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

Background Surgery-induced neuroinflammation plays an important role in postoperative
cognitive dysfunction (POCD). Gut microbiota is a key regulator of neurological …

This umbrella review aimed to systematically identify the peri-operative risk factors
associated with post-operative cognitive dysfunction (POCD) using meta-analyses of …

Surgical trauma can induce an inflammatory response in the central nervous system.
Neuroinflammation is a crucial pathological mechanism of perioperative neurocognitive …

The perioperative neurocognitive disorders (PNDs) are one of the most common
complications in elderly patients characterized by various forms of cognitive decline after …