Role of miRNAs in diabetic neuropathy: mechanisms and possible interventions

P Kaur, S Kotru, S Singh, A Munshi - Molecular neurobiology, 2022 - Springer
Accelerating cases of diabetes worldwide have given rise to higher incidences of diabetic
complications. MiRNAs, a much-explored class of non-coding RNAs, play a significant role …

Role of DNA methyl-CpG-binding protein MeCP2 in Rett syndrome pathobiology and mechanism of disease

S Pejhan, M Rastegar - Biomolecules, 2021 - mdpi.com
Rett Syndrome (RTT) is a severe, rare, and progressive developmental disorder with
patients displaying neurological regression and autism spectrum features. The affected …

Increased miR-132-3p expression is associated with chronic neuropathic pain

M Leinders, N Üçeyler, RA Pritchard, C Sommer… - Experimental …, 2016 - Elsevier
Alterations in the neuro-immune balance play a major role in the pathophysiology of chronic
neuropathic pain. MicroRNAs (miRNA) can regulate both immune and neuronal processes …

Emerging role of microRNAs in major depressive disorder and its implication on diagnosis and therapeutic response

L Zhou, Y Zhu, W Chen, Y Tang - Journal of Affective Disorders, 2021 - Elsevier
Background: Major depressive disorder (MDD) is a serious and common psychiatric
disorder with a high prevalence in the population. Although great advances have been …

Role of microRNA in governing synaptic plasticity

Y Ye, H Xu, X Su, X He - Neural Plasticity, 2016 - Wiley Online Library
Although synaptic plasticity in neural circuits is orchestrated by an ocean of genes,
molecules, and proteins, the underlying mechanisms remain poorly understood. Recently, it …

[HTML][HTML] Epigenetic landscapes of pain: DNA methylation dynamics in chronic pain

HY Xiong, A Wyns, JV Campenhout, J Hendrix… - International Journal of …, 2024 - mdpi.com
Chronic pain is a prevalent condition with a multifaceted pathogenesis, where epigenetic
modifications, particularly DNA methylation, might play an important role. This review delves …

The etiological roles of miRNAs, lncRNAs, and circRNAs in neuropathic pain: a narrative review

M Jiang, Y Wang, J Wang, S Feng… - Journal of clinical …, 2022 - Wiley Online Library
Abstract Background Non‐coding RNAs (ncRNAs) are involved in neuropathic pain
development. Herein, we systematically searched for neuropathic pain‐related ncRNAs …

Increased cutaneous miR-let-7d expression correlates with small nerve fiber pathology in patients with fibromyalgia syndrome

M Leinders, K Doppler, T Klein, M Deckart, H Rittner… - Pain, 2016 - journals.lww.com
Fibromyalgia syndrome (FMS) is a chronic widespread pain condition probably comprising
subgroups with different underlying pathomechanisms. There is increasing evidence for …

MBD1 contributes to the genesis of acute pain and neuropathic pain by epigenetic silencing of Oprm1 and Kcna2 genes in primary sensory neurons

K Mo, S Wu, X Gu, M Xiong, W Cai… - Journal of …, 2018 - Soc Neuroscience
The transmission of normal sensory and/or acute noxious information requires intact
expression of pain-associated genes within the pain pathways of nervous system …

[HTML][HTML] The role of micro-RNAs in neuropathic pain—a scoping review

KK Sampath, S Belcher, J Hales, OP Thomson… - Pain …, 2023 - journals.lww.com
1. Background Chronic pain is a major clinical challenge with an incidence of 20% to 25%
among the adult population worldwide, often reducing the quality of social and work life. 9 …