Outbreaks of severe virus infections with the potential to cause global pandemics are
increasing. In many instances these outbreaks have been newly emerging (SARS …

Abstract Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–
Barr virus (EBV) infection, and has since emerged as the crucial regulator of type I …

Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish
asymptomatic life-long persistence. It is associated with a large spectrum of diseases …

Advances in innate immunity over the past decade have revealed distinct classes of pattern
recognition receptors (PRRs) that detect pathogens at the cell surface and in intracellular …

Interferon regulatory factor (IRF) 7 was originally identified as master transcriptional factor
that produced IFN-I and regulated innate immune response, subsequent studies have …

Epstein-Bar virus (EBV) is widespread within the human population with over 90% of adults
being infected. In response to primary EBV infection, the host mounts an antiviral immune …

Viral infection triggers an early host response through activation of pattern recognition
receptors, including Toll-like receptors (TLR). TLR signaling cascades induce production of …

Mediators of the initiation, development, and recurrence of periodontitis include the oral
microbiome embedded in subgingival plaque and the host immune response to a dysbiosis …

Epstein‒Barr virus (EBV) is a DNA virus that belongs to the human B lymphotropic
herpesvirus family and is highly prevalent in the human population. Once infected, a host …

Abstract IFN regulatory factor 7 (IRF7) is a potent transcription factor of type I IFNs and IFN-
stimulated genes and is known as the master regulator of type I IFN-dependent immune …