[HTML][HTML] IL-12 family cytokines in cancer and immunotherapy

B Mirlekar, Y Pylayeva-Gupta - Cancers, 2021 - mdpi.com
Simple Summary The IL-12 family cytokines play an important role in regulating the tumor
immune contexture. Recent efforts geared towards the development of better immune …

Tumor-elicited inflammation and colorectal cancer

K Wang, M Karin - Advances in cancer research, 2015 - Elsevier
The link between chronic inflammation and cancer has long been suspected, due to the
pioneering work of Rudolf Virchow over 150 years ago. Yet the causal relationship between …

[HTML][HTML] Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells

S Li, X Cong, H Gao, X Lan, Z Li, W Wang… - Journal of Experimental …, 2019 - Springer
Purpose Epithelial to mesenchymal transition (EMT) can contribute to gastric cancer (GC)
progression and recurrence following therapy. Tumor-associated neutrophils (TANs) are …

Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells

X Wang, L Yang, F Huang, Q Zhang, S Liu, L Ma… - Immunology letters, 2017 - Elsevier
Programmed cell death protein 1 (PD-1) acts on PD-1 ligands (PD-L1 and PD-L2) to
suppress activation of cytotoxic T lymphocytes. Interleukin-17 (IL-17) and tumor necrosis …

[HTML][HTML] In vitro and in vivo model systems used in prostate cancer research

D Cunningham, Z You - Journal of biological methods, 2015 - ncbi.nlm.nih.gov
New incidence of prostate cancer is a major public health issue in the Western world, and
has been rising in other areas of the globe in recent years. In an effort to understanding the …

Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition

Q Zhang, S Liu, KR Parajuli, W Zhang, K Zhang, Z Mo… - Oncogene, 2017 - nature.com
Chronic inflammation has been associated with a variety of human cancers including
prostate cancer. Interleukin-17 (IL-17) is a critical pro-inflammatory cytokine, which has been …

[HTML][HTML] Cellular and molecular progression of prostate cancer: models for basic and preclinical research

S Saranyutanon, SK Deshmukh, S Dasgupta, S Pai… - Cancers, 2020 - mdpi.com
Simple Summary The molecular progression of prostate cancer is complex and elusive.
Biological research relies heavily on in vitro and in vivo models that can be used to examine …

[HTML][HTML] IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC

JH Kang, S Park, J Rho, EJ Hong, YE Cho, YS Won… - Gastric Cancer, 2023 - Springer
Background Gastric cancer (GC) is a common malignancy worldwide, with a major
attribution to Helicobacter pylori. Interleukin (IL)-17A has been reported to be up-regulated …

The role of prostatic inflammation in the development and progression of benign and malignant diseases

G Gandaglia, E Zaffuto, N Fossati… - Current opinion in …, 2017 - journals.lww.com
Men with BPH-related lower urinary tract symptoms and chronic prostatic inflammation
should be considered at increased risk of symptom progression and acute urinary retention …

A comprehensive review of immunotherapies in prostate cancer

MC Maia, AR Hansen - Critical reviews in oncology/hematology, 2017 - Elsevier
Prostate cancer is the second most common malignant neoplasm in men worldwide and the
fifth cause of cancer-related death. Although multiple new agents have been approved for …